Background and objectives: Pain is a primarily protective in nature, but often causes discomfort. Currently available analgesic drugs are not useful in all cases due to their side effects. Medicinal plants are believed to be an important source of new chemical substances with potential therapeutic effects, such as, Teucrium polium (TP) used traditionally to relieve hea...

The main function of the cardiac adrenergic system is to regulate cardiac work both in physiologic and pathologic states. A better understanding of this system has permitted the elucidation of its role in the development and progression of heart failure. Regardless of the initial insult, depressed cardiac output results in sympathetic activation. Adrenergic receptors provide a limiting step to ...

Adrenergic and cholinergic tone on the cardiovascular system of embryonic chickens was determined during days 12, 15, 19, 20, and 21 of development. Administration of the muscarinic antagonist atropine (1 mg/kg) resulted in no significant change in heart rate or arterial pressure at any developmental age. In addition, the general cardiovascular depressive effects of hypoxia were unaltered by pr...

Heteronuclear NMR in combination with isotope labelling is used to study folding of polypeptides induced by metals the case metallothioneins, binding peptidic allosteric modulator ?-TIA human G-protein coupled ?1b adrenergic receptor, development therapeutic drugs that interfere biosynthesis outer membrane Gram-negative bacteria, and a system which protein assembly upon peptide addition. these ...

Different beta 1 and 2 adrenergic receptor agonists may be various biological and physiological effects on fish species. An experiment was designed to study the effects of feeding ractopamine, terbutaline and metaproterenol; as beta1, beta2 and less selective beta 2 adrenergic receptor agonists, respectively; on body weight gain, feed conversion ratio, concentration of biochemical parameters in...

The effects of epidermal growth factor (EGF) on the beta-adrenergic receptor-coupled adenylyl cyclase system were studied in a human salivary cell line (HSY). The beta-adrenergic agonist isoproterenol (10(-5) M) stimulated adenylyl cyclase activity by approximately 2-fold, and the isoproterenol response was increased 1.8-fold after prolonged (48 h) exposure to EGF (5 x 10(-10) M). In contrast, ...