Background
 Nicotine consumption during pregnancy and advanced maternal age are well known independent risk factors for poor outcome therefore serious public health problems.
 Objectives
 Considering the ongoing trend of delaying childbirth in our society, this study investigates potential additive effects nicotine on foetal growth.
 Sample Methods
 In a medical record-...

This study analyzes the association between advanced maternal age and increased incidence of Down syndrome in neonates, based on a population sample from the State of Bahia in Northeast Brazil. Age of the mothers of 220 Down syndrome subjects was investigated, and age distribution was compared to that of the population control group, 220 mothers of subjects without Down syndrome. The proportion...

OBJECTIVE To assess the association between advanced maternal age (AMA) and adverse pregnancy outcomes. DESIGN Secondary analysis of the facility-based, cross-sectional data of the WHO Multicountry Survey on Maternal and Newborn Health. SETTINGS A total of 359 health facilities in 29 countries in Africa, Asia, Latin America, and the Middle East. SAMPLE A total of 308 149 singleton pregnan...

Objectives: To study whether advanced maternal age and maternal grandmother age are associated with increased risk of Down syndrome siblings in a group of Jordanian families. Methods: This study was conducted on 127 confirmed Down syndrome cases with the age range of 18 weeks gestation to 15 years old, which were referred between the period of 2005-2008 for cytogenetic analysis at the Cytogenti...

INTRODUCTION Women older than 40 years have been termed "advanced maternal age" and considered to be at risk of adverse pregnancy outcome. This study aimed to examine the obstetrical outcomes among primiparous and multiparous African advanced maternal age women. METHODS We conducted a retrospective cohort study study at two teaching hospitals at Yaounde, Cameroon. From the hospital records, o...

background: women 35-39 years old have a 2–3 fold higher risk of pregnancy-related death than women in their twenties and the risk is even more dramatic for women 40 years and older. objective: the aim of this study was to investigate the association of maternal age with risk of adverse pregnancy and mother outcomes in our setting tehran iran. materials and methods: in this retrospective observ...

Multiple gestations are associated with an increased risk of maternal morbidity and mortality independent of maternal age. Previous reports by the Canadian Institute for Health Information established the overall association between advanced maternal age and complications related to pregnancy and childbirth. This article takes a more focused look at the association between advanced maternal age...