Bone has a capability to repair itself when it is fractured. Repair involves the generation of intermediatetissues, such as fibrous connective tissue, cartilage and woven bone, before final bone healing can occur. Theprocess of cartilage-to-bone transition (CBT) is a key for the achievement of rigid bone healing duringfracture repair. We tested this potential for elastic cartilage using a long ...

Self-healing technology offers an autonomic route to repairing damage in advanced polymers to extend their lifetime. A variety of self-healing systems have been developed for mechanical self-healing, protective coatings, and electronic self-healing. These self-healing systems rely on functional groups within the polymer, microvascular networks, or compartmentalization in capsules and particles....

Designing self-healing into cementitious materials can open a new world of opportunities for resilient concrete infrastructure under service loading conditions. The self-healing process should be robust as well as repeatable, allowing for self-repair after multiple damage events. The repeatability poses great challenges when self-healing strategies mainly rely on the formation of low-strength c...

Wound healing is an inherent feature of any multicellular organism and recent years have brought about a huge amount of data regarding regular and abnormal tissue repair. Despite the accumulated knowledge, modulation of wound healing is still a major biomedical challenge, especially in advanced ages. In order to collect and systematically organize what we know about the key players in wound hea...

OBJECTIVE Elephantiasis nostras is a rare complication in advanced lipo-lymphedema. While lipedema can be treated by liposuction and lymphedema by decongestive lymphatic therapy, elephantiasis nostras may need debulking surgery. METHODS We present 2 cases of advanced lipo-lymphedema complicated by elephantiasis nostras. After tumescent microcannular laser-assisted liposuction both patients un...

Wound healing is critical to prevent complications, such as infections, delayed healing, and misshapen scars, promote optimal recovery of damaged tissue. Proper wound evaluation, proper cleaning, debridement, use dressings, nutrition hydration, infection prevention treatment, inflammation control, advanced therapies are all important measures consider in care.

Background: This two-arm, randomized clinical study aimed to compare efficacy between topical Alpha ointment and topical hydrocortisone cream (1%) in the healing of radiation-induced dermatitis in breast cancer patients. Methods: The inclusion criteria comprised newly pathologically proven, locally advanced breast cancer (treated with modified radical mastectomy followed by sequential adjuvant ...