Ischemically sensitive visceral sympathetic nerve fibers, which are thought to represent the afferent limb of a strong cardiovascular pressor reflex, can be stimulated by exogenously applied bradykinin (BK). During ischemia, BK also is known to be produced locally and to serve as an endogenous stimulus for activation of ischemically sensitive nerve endings. It is unclear, however, whether ische...

The hydrolysis of bradykinin (Bk) by different classes of proteases in plasma and tissues leads to a decrease in its half-life. Here, Bk actions on smooth muscle and in vivo cardiovascular assays in association with a protease inhibitor, Black eyed-pea trypsin and chymotrypsin inhibitor (BTCI) and also under the effect of trypsin and chymotrypsin were evaluated. Two synthetic Bk-related peptide...

Proton and fluorine nuclear magnetic resonance spectroscopies (NMR) were used as methods to investigate binary complexes between porcine adenylate kinase (AK1) and its substrates. We also studied the interaction of fluorinated substrate analogues and the supposed bisubstrate analogue P1,P5-bis(5'-adenosyl) pentaphosphate (AP5A) with AK1 in the presence of Mg2+. The chemical shifts of the C8-H, ...

BACKGROUND Mitochondria, which are essential for the functionality of eukaryotic cells, are particularly important in metabolically active tissues such as liver. Different breeds of pigs demonstrate distinct metabolic profiles in the liver, yet little is known whether the expression and transcriptional regulation of mitochondrial genes differ between breeds. RESULTS Here we used male newborn ...

We review some results about the first eigenvalue of the infinity Laplacian operator and its first eigenfunctions in a general norm context. Those results are obtained in collaboration with several authors: V. Ferone, P. Juutinen and B. Kawohl (see [BFK], [BK1], [BJK] and [BK2]). In section 5 we make some remarks on the simplicity of the first eigenvalue of ∆∞: this will be the object of a join...

Anoxybacillus flavithermus strain AK1 was isolated from Al-Ain Alhara, a thermal hot spring located 50 km southeast of the city of Gazan, Saudi Arabia (16°56'N, 43°15'E). The sequenced and annotated genome is 2,630,664 bp and encodes 2,799 genes.

We show that a fast algorithm for the QR factorization of a Toeplitz or Hankel matrix A is weakly stable in the sense that RR is close to AA. Thus, when the algorithm is used to solve the semi-normal equations RRx = A b, we obtain a weakly stable method for the solution of a nonsingular Toeplitz or Hankel linear systemAx = b. The algorithm also applies to the solution of the full-rank Toeplitz ...

Vsx-1 is a paired-like:CVC homeobox gene whose expression is linked to bipolar cell differentiation during zebrafish retinogenesis. We used a yeast two-hybrid screen to identify proteins interacting with Vsx-1 and isolated Ubc9, an enzyme that conjugates the small ubiquitin-like modifier SUMO-1. Despite its interaction with Ubc9, we show that Vsx-1 is not a substrate for SUMO-1 in COS-7 cells o...

1. Fundamental theorem. In a recent paper f I have proved the theorem that if a lacunary trigonometric series CO (1) X(a* cos nk6 + bk sin nk9) (nk+x/nk > q > 1, 0 ^ 0 ^ 2ir) 4-1 has its partial sums uniformly bounded on a set of 0 of positive measure, then the series (2) ¿(a*2 + bk2) k-l converges. The proof was based on the following lemma (which was not stated explicitly but is contained in ...