نتایج جستجو برای: albumin and globulinconcentrations
تعداد نتایج: 16832543 فیلتر نتایج به سال:
Human serum albumin is one of the most important blood proteins that has the ability to bind a wide range of compounds and different drugs. Hence, knowing how drugs bind to albumin is crucial to understand their pharmacokinetics and pharmacodynamic properties. The binding of drugs to protein affects the drug's excretion, distribution and interaction in the target tissues. Nicotinamide (NA) is a...
background: administration of albumin for burn patients and its effects on mortality and morbidity has been debated for along time. the aim of this study was to evaluate the effects of albumin administration on wound healing, length of hospital stay, weight change, and mortality of burn patients. methods: two matched groups of patients from shiraz burn care center were randomly selected. the ...
Nephrotic syndrome is an important disease in children and the diagnosis and treatment of its complications is important. Edema is one of these complications which is more common and severe in children and has different treatment in comparison with adults. Treatment of edema in children contains protocols that increase intravascular volume and decrease sodium reabsorption in all par...
interaction of drugs with serum albumin, the most abundant protein in plasma, has a great significance in pharmaceutical sciences. it can affect the biological activity, toxicity, and pharmacokinetics of drugs and design of dosages. determination of the impact of chemical modifications of albumin and its structural changes upon interaction with drugs are very important when drugs bind with albu...
Background and Objective: Mortality of hemodialysis patients is still high, which can be estimated using the Charlson Comorbidity Index (CCI) and serum albumin. Materials and Methods: This prospective cohort study was conducted on adult chronic hemodialysis patients (n=532) from 9 hemodialysis (HD) facilities in September 2012. The obtained data included demographic factors and laboratory data...
Background: Hepatitis B (HB) vaccination is a recommended procedure in all dialysis patients, but its efficacy has not been perfect. In the current study, we aimed to conduct a comprehensive review of the literature to find and pool data of the randomized trials evaluating the impact of serum albumin levels on the immunogenicity of HB vaccination in dialysis patients. Methods: Literature searc...
Background: Albumin is known as a human blood product, with high cost and limited availability. Several studies have demonstrated the extent in which albumin is being utilized in controversial indications not supported or weakly supported by the available literature. Objective: To rationalize the use of albumin and to decrease the inappropriate cost of this expensive drug. Methods: A two phase...
human serum albumin has been used as a model protein for protein folding and ligand binding studies over many decades. due to its long life period and high concentration in plasma, hsa is highly sensitive to glycation. it is reported that 175 mg/dl glucose concentration is a threshold of kidney activity for the beginning of excretion of glucose. ph denaturation of hsa in absence and presence of...
introduction : albumin, one of the most important plasma proteins, has a difficult process of synthesis and production. we compared two different methods for albumin purification: carboxymethyl cellulose (cm cellulose) resin exchange and diethylaminoethyl cellulose (deae cellulose) resin exchange in order to determine which resin could be more beneficial. materials and methods : two ion exchang...
Albumin is a protein macromolecule that it has been attractive since the early 20th century and has several therapeutic applications. Albumin is an aboundant serum with good biocompatibility, hematopoiesis and biodegradability in blood. The existence of multiple functional groups makes it possible to carry significant amounts of therapeutic and diagnostic factors, as well as targeting factors. ...
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