نتایج جستجو برای: all t
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two igm monoclonal antibodies (mab) with strong reactivity for granulocytes and to a lesser extent for lurkat cell lines were established by immunizing balbi c mice with a histiocytic cell line (uy37). these two mabs (designated as 6c9 and 4c4) reacted with blast cells of t-acute lymphoblastic leukemia (t-all) and acute myelogenous leukemia (aml) patients as well as leukemic cells from patients...
The calcineurin/NFAT signaling pathway is implicated in a wide variety of biological processes, acting as a bridge pathway between calcium signals and gene expression. Although its role as an effector of immune responses figured prominently in early studies, it forms just one part of a larger picture. Indeed calcineurin has been shown to participate in the development and function of e.g. the i...
In these talks I’ll try to explain these classes of groups so peculiarly separated by chance. I’ll start in § 1 with amenable groups, which have been studied the longest (since von Neumann in the 1920s, who was investigating the Banach–Tarski paradox as Henry explained last term), and are a very natural class of groups to look at. Then I’ll move on in § 2 to an enormous superset of the amenable...
The molecular mechanisms involved in disease progression and relapse in T-cell acute lymphoblastic leukemia (T-ALL) are poorly understood. We used single nucleotide polymorphism array analysis to analyze paired diagnostic and relapsed T-ALL samples to identify recurrent genetic alterations in T-ALL. This analysis showed that diagnosis and relapsed cases have common genetic alterations, but also...
The data reported in this paper use a mouse model system where either the activated form of Notch1 (NotchIC) or c-Myc is under the control of the Tet operator and inducible by removal of doxycycline from the drinking water. Induction of either NotchIC or c-Myc is sufficient to drive the formation of T-cell leukemias that resemble human T-ALL. The authors have also used retroviral expression vec...
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