In a previous article, I discussed adverse drug reactions (ADRs) attributed to statin therapy, specifically myopathies, as well as potential consequences and recommended alternatives. These ADRs are not trivial because they may lead to patient harm in severe cases and/or significant patient nonadherence in most cases. In fact, statins are frequently discontinued as a result of ADRs1,2 and for a...

In a previous article, I discussed adverse drug reactions (ADRs) attributed to statin therapy, specifically myopathies, as well as potential consequences and recommended alternatives. These ADRs are not trivial because they may lead to patient harm in severe cases and/or significant patient nonadherence in most cases. In fact, statins are frequently discontinued as a result of ADRs1,2 and for a...

Calorie restriction (CR) and alternate-day fasting (ADF) represent 2 different forms of dietary restriction. Although the effects of CR on chronic disease prevention were reviewed previously, the effects of ADF on chronic disease risk have yet to be summarized. Accordingly, we review here animal and human evidence concerning ADF and the risk of certain chronic diseases, such as type 2 diabetes,...