نتایج جستجو برای: aminobenzoic acid
تعداد نتایج: 747482 فیلتر نتایج به سال:
The fact that urethane, a structurally unrelated compound, can inhibit sulfanilamide action has caused Johnson (1942) to question the competitive metabolite hypothesis developed by McIntosh and Whitby (1939), Stamp (1939), Fildes (1940), Green (1940), Woods (1940) and Woods and Fildes (1940). He would explain the antagonism of p-aminobenzoic acid on the basis of the well-known fact that narcoti...
The biosynthesis of candicidin has been studied with various carbon-14 labeled precursors. The aromatic moiety of candicidin is evidently synthesized from glucose via shikimate to ^-aminobenzoic acid, which is then incorporated into candicidin. The synthesis of candicidin was partially inhibited by the presence of L-phenylalanine, L-tryptophane and L-tyrosine in the growing culture. The implica...
A screening method was established to detect inhibitors of the biosynthetic pathways of aromatic amino acids and para-aminobenzoic acid, the precursor of folic acid, using an agar plate diffusion assay modified as an antagonism test. By this screening method, a family of three novel polycyclic polyketides named as abyssomicins was isolated from a marine strain of Verrucosispora. The main compon...
The formation of folic acid compounds from pteridines and p-aminobenzoic acid by whole bacterial cells has been studied by Korte et al. (1, 2), who reported that C%xanthopterin (2-amino4,6-dihydroxypteridine) could be incorporated into folic acid by several bacterial species, and by Weygand et al. (3), who found that certain strains of bacteria can be adapted to utilize 2.amino-4-hydroxy-6-form...
1. Chronic renal failure was induced in rats by surgical removal of thirteen-sixteenths of renal tissue. 2. The metabolism of p-amino[14C]benzoic acid was studied in the isolated perfused livers of control and chronically uraemic rats. There was a slower rate of clearance and decreased overall metabolism of the compounds in the uraemic rats. 3. Conjugation of p-amino[14C]benzoic acid with glyci...
Analytical recovery of urinary p-aminobenzoic acid liberated from bentiromide(N-benzoyl-L-tyrosyl-p-aminobenzoicacid) was determinedby roomtemperaturephosphorimetryas an index to exocrine pancreatic function. Metabolites were hydrolyzed to the parent compound in 4 mol/L NaOH, then quantified, after pH adjustment, by spothng 3 L of this solution onto filter paper treated with potassium iodide an...
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