background & objectives: one of the important infectious factors in pregnant mothers and newborns is group b streptococcus (gbs). there is no perfect report about prevalence of gbs in iran and in the case of preterm rupture of amniotic membrane or preterm labor all patients are treated by antibiotics without culture so this has led to adverse taking antibiotics and drug resistance. the pres...

Amniotic membrane is applied to the diseased ocular surface to stimulate wound healing and tissue repair, because it releases supportive growth factors and cytokines. These effects fade within about a week after application, necessitating repeated application. Generally, amniotic membrane is fixed with sutures to the ocular surface, but surgical intervention at the inflamed or diseased site can...

purpose: to develop a nanofibrous polycaprolacton (pcl) substrate for limbal stem cell (lsc) expansion that can serve as a potential alternative substrate to replace human amniotic membrane. methods: the human limbal stem cells (lscs) were used to evaluate the biocompatibility of substrates (nanofibrous scaffold, and human amniotic membrane) regarding cellular phenotypic profile, viability, pro...

Cryopreserved amniotic membrane modulates adult wound healing by promoting epithelialization while suppressing stromal inflammation, angiogenesis and scarring. Such clinical efficacies of amniotic membrane transplantation have been reported in several hundred publications for a wide spectrum of ophthalmic indications. The success of the aforementioned therapeutic actions prompts investigators t...

Human amniotic membrane as a homograft material was compared to temporalis fascia to close tympanic membrane perforations in 50 patients with chronic otitis media. Human amniotic membrane was used in 20 patients while temporalis fascia was used in the remaining 30. Anatomical closure of the perforation and reduction of the air-bone gap was measured. The graft uptake showed a 65% success rate fo...

Introduction: Amniotic membrane, the innermost layer of extra-embryonic tissue, contains mesenchymal and epithelial stem cells. The amniotic mesenchymal cells have the capability of inhibition of growth of cancer cells. In this research, the effects of amniotic epithelial cells on the viability of cancer cells and the role of apoptosis in this procedure were evaluated. Methods: Amniotic mem...

PURPOSE Amniotic membrane transplantation is currently being used as an alternative approach to treat severe corneal surface disorders refractory to medical therapy. The authors report complications of corneal surface disorders after successful amniotic membrane transplantation. METHODS Case series. RESULTS Twenty-eight patients with corneal surface disorders due to severe chemical burns, c...

amniotic epithelial cells (aecs) possess unique characteristics, which make them a suitable source for cell-based therapeutic strategies. aecs have stem cell properties with low-immunogenicity (due to expressing hla-g molecule and absence of mhc class i and ii antigens) and no ethical problems, as well as availability in sufficient numbers, which can be obtained from a placenta. we have recentl...