OBJECTIVES The illicit use of anabolic steroids among the gym population continues to rise, along with the number of steroid using clients attending harm reduction services in the UK. This presents serious challenges to public health. Study objectives were to account for the experiences of anabolic steroid users and investigate how 'risk environments' produce harm. METHODS Qualitative face-to...

We report a 42-year-old male amateur body builder and user of anabolic androgenic steroids, who developed ARDS, acute kidney injury, and refractory supraventricular tachycardia. He required extracorporeal membrane oxygenation, continuous veno-venous hemodialysis, and catheter ablation. We believe that long-term anabolic androgenic steroid abuse predisposed the patient to multiple organ dysfunct...

Phytoecdysteroids are structural analogs of the insect molting hormone ecdysone. Plants comprise rich sources of ecdysteroids in high concentration and with broad structural diversity. Ecdysteroids have a number of proven beneficial effects on mammals but the hormonal effects of ecdysteroids have been proven only in arthropods. Their structures are somewhat similar to those of the vertebrate st...

Use of anabolic steroids has for some time been widespread among competitive sportsmen and women, who selfadminister doses of up to 100 times the recommended therapeutic dose, and use combinations of multiple oral and injectable preparations (a practice known as'stacking'). Often these are preparations intended for veterinary use, or of questionable origin, purity or authenticity. They are take...

A 66-year-old male patient developed jaundice after 7 months of treatment with the anabolic steroid, stanozolol. When the drug was withdrawn he made a full and uneventful recovery. A liver biopsy showed the histology of a hypersensitivity reaction. This is believed to be the first time jaundice has been recorded with stanozolol therapy and the first time a hypersensitivity-type jaundice has bee...

In addition to the pharmacological side effects of anabolic steroids, complications may also result from the injection technique used in self administration. Two cases are presented where anabolic steroid injections resulted in knee joint sepsis and radial nerve palsy.

BACKGROUND: Hip fracture occurs predominantly in older people, many of whom are frail and undernourished. After hip fracture surgery and rehabilitation, most patients experience a decline in mobility and function. Anabolic steroids, the synthetic derivatives of the male hormone testosterone, have been used in combination with exercise to improve muscle mass and strength in athletes. They may ha...

BACKGROUND To date, no studies document the effect of anabolic steroids on rotator cuff tendons. STUDY DESIGN Controlled laboratory study. HYPOTHESIS Anabolic steroids enhance remodeling and improve the biomechanical properties of bioartificially engineered human supraspinatus tendons. METHODS Bioartificial tendons were treated with either nandrolone decanoate (nonload, steroid, n = 18), ...