Objectives: The objective of this study is: To determine frequency of persistent postoperative incontinence in closed lateral internal sphincterotomy for chronic anal fissure. Study design: Descriptive study (Case series). Place and duration: The study was undertaken at the department of the General Surgery, Nishtar Hospital Multan from Nov5,2008 to May 5, 2009. Material and methods: One hundre...

4 刘凤斌 , 赵 利 . 建立中医疗效测评量表体系研究的设 想[ J] . 中国临床康复 , 2004 , 8 (1 ) : 164-165 . 5 郭新峰 , 赖世隆 , 梁伟雄 . 中医药临床疗效评价中结局 指标的选择与应用 [ J ] . 广州中医药大学学报 , 2002 , 19( 4) : 251-255 . 6 Fleming TR , DeMets DL . Surrogate end poin ts in clinical tr ials : are we being mislead ? [ J ] . Ann Inte rn Med , 1996 , 125( 7) : 605-613 . 7 赖世隆 , 胡镜清 , 郭新峰 . 循证医学与中医药临床研究 [ J] . 广州中医药大学学报 , 2000 , 17(1 ) : 1-8 . 8 宋 军 , 陈可冀 . ...

Major advances in our understanding of the mechanisms involved in chronic anal fissure have allowed the introduction of many new medical therapies for this condition. The literature about current treatment modalities licensed for anal fissure and those novel therapies still under evaluation has been reviewed. These new treatments are examined in the context of traditional surgical management of...

INTRODUCTION Anal fissure is an ischemic ulcer caused by combination of spasm of internal anal sphincter and poor blood supply to the posterior midline of anal canal. This study aimed to assess the efficacy of Glyceryl Trinitrate and Nifedipine in the treatment of chronic anal fissure. METHODS Ninety patients with symptomatic anal fissure in Kathmandu Medical College Teaching Hospital are all...

OBJECTIVE To compare the symptomatic relief, healing and side-effects of topical diltiazem (DTZ) and glyceryl trinitrate in the treatment of chronic anal fissure. STUDY DESIGN Randomized controlled trial. PLACE AND DURATION OF STUDY The Surgical Outpatient Department of Civil Hospital, Karachi, from March 2006 to February 2007. METHODOLOGY Patients with chronic anal fissure were included ...

Background: The presence of Hypertrophied anal papillae and fibrous anal polyps are often ignored in the proctology practice. But the experience is that they tend to produce minor but disturbing symptoms. This study is aimed to assay the impact and utility of attending to these two conditions concurrently while dealing with cases of fissure in ano. Material and Methods: A study was carried out ...

BACKGROUND Medical sphincterotomy has gained popularity as a treatment for anal fissure. Calcium channel blockers in topical forms could also be appropriate with low adverse effects. OBJECTIVES This was a prospective randomized controlled trial to compare topical and oral nifedipine in the treatment of chronic anal fissure. PATIENTS AND METHODS A prospective randomized controlled trial was ...

chronic anal fissure is the most common cause of anal pain associated with internal anal sphincter hypertonia. reduction of hypertonocity is a special treatment for fissure healing. for this purpose chronic anal fissures were conventionally treated by anal dilatation or by lateral sphincterotomy. however, both of these methods may cause a degree of incontinence in some patients. the uptake of m...