INTRODUCTION The incidence of anaphylactic reactions during anesthesia is between 1:5000 and 1:25000 and it is one of the few causes of mortality directly related to general anesthesia. The most important requirements in the treatment of this clinical condition are early diagnosis and maintenance of vital organ perfusion. Epinephrine administration is generally considered as the first line trea...

BACKGROUND Hydatid disease, a parasitic infestation of humans, is endemic in the Mediterranean region, Australia, New Zealand and the Middle East, and mostly involves the liver. Anaphylactic reactions, which sometimes are the first manifestations of the disease, frequently occur due to cyst rupture after a minor/major trauma, though they may also be spontaneously seen on rare occasions. In extr...

BACKGROUND Lymphazurin 1% blue dye can cause a severe anaphylactic reaction in approximately 1-3% of patients. CASE PRESENTATION We describe a case of intraoperative anaphylaxis resulting from Lymphazurin 1% blue dye. A 48-year old woman undergoing a mastectomy with sentinel lymph node biopsy experienced a biphasic anaphylactic reaction with two episodes of hypotension at 15 minutes and 2 hou...

Addition of specific antigen to the isolated atria of sensitized guinea pigs and of histamine to those of nonsensitized animals resulted in an increase of both frequency and amplitude of contraction and in the appearance of rhythmic activity in the isolated left atrium. On a quantitative basis the anaphylactic response looks like the effects of histamine in concentrations between 10~ and 10~ mM...

1. The antitryptic titer of the serum can be increased by subcutaneous injections of serum lipoids (antitrypsin) and of the lipoids from egg yolk. 2. Animals so injected show a relative immunity to acute anaphylactic shock (two minimum lethal doses). 3. Extraction of lipoids contained in antigens increases the toxicity of the antigen when injected into a sensitized animal. 4. Sublethal doses of...

1. The type-specific carbohydrates (haptens) of Pneumococcus Types I, II and III, when isolated in protein-free form, are devoid of the property of inducing active anaphylactic sensitization in guinea pigs. 2. The bacterial carbohydrates of Pneumococcus, of which the Type II and Type III substances are nitrogen-free, produce rapid and fatal anaphylactic shock in guinea pigs passively sensitized...

Chlorhexidine is a common antiseptic and disinfectant used in the medical field. Allergy to chlorhexidine has been reported in the literature but life-threatening anaphylactic shock is rare. We present a case of severe anaphylactic shock due to chlorhexidine occurring during surgery. Literatures suggest that profound anaphylactic shock to chlorhexidine is commonly preceded by milder, non-specif...

introduction diabetic foot is a clinical disorder, which is commonly seen in patients with diabetes mellitus. it is also the major cause of below knee amputation in the world. there are many underlying causes such as neuropathic, ischemic, and infectious causes for diabetic foot. local or systemic complications may develop after snake bite. case presentation we reported a very rare case, involv...

In the present study, anti-anaphylactic, anti-inflammatory and membrane stabilizing properties of a lupine alkaloid plumerianine (compound 1), isolated from the root bark of Plumeria acutifolia Poir were investigated in animal models. The anti-anaphylactic activity of compound 1 (10, 25 and 50 mg/Kg) was studied by using models such as passive cutaneous anaphylaxis, passive paw anaphylaxis and ...