نتایج جستجو برای: and 5106 cellml

تعداد نتایج: 16827192  

Journal: :Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 2008
Alan Garny David P Nickerson Jonathan Cooper Rodrigo Weber dos Santos Andrew K Miller Steve McKeever Poul M F Nielsen Peter J Hunter

We have, in the last few years, witnessed the development and availability of an ever increasing number of computer models that describe complex biological structures and processes. The multi-scale and multi-physics nature of these models makes their development particularly challenging, not only from a biological or biophysical viewpoint but also from a mathematical and computational perspecti...

Journal: :Physiome 2023

The system of equations and figures presented in the primary paper (Lees Green et al, 2014) are verified reproduced this paper’s curation effort. We describe here model encoding CellML format document differences between published to demonstrate reproducibility.

Journal: :IET systems biology 2008
M T Cooling P Hunter E J Crampin

In recent years advances in the construction of mathematical models of biological systems have yielded an array of valuable constructs. The authors seek to provide a 'leading practice' method for implementing modularised kinetic mass-action models in order to obtain a number of advantages in model construction, validation and derived insights. The authors advocate the consideration of 'accounti...

Journal: :Bioinformatics 2008
David P. Nickerson Alberto Corrias Martin L. Buist

UNLABELLED In recent years there has been much development of the fundamental ideas underlying mathematical model curation in regard to models of biology. While much has been achieved in the realms of systems biology and bioinformatics, little progress has been made in relation to cellular electrophysiology modeling. The primary reason for slow progress in this field is the lack of a consistent...

2006
Yong Xie Mila Katzarova Tom Melham Duncan Coutts Ivan Flechais Luke Ong Vasile Palade Blanca Rodriguez Andrew Simpson

Understanding the human heart is a subject of much interest. Heart problems are a majorcause of death in developed countries, and much effort has been put into elucidating thecauses of heart disease in the hope of developing cures. Many drugs also have adverse sideeffects on the heart, which drug companies would like to avoid.Computer simulations have played an important part in...

Journal: :Frontiers in Bioengineering and Biotechnology 2015

Journal: :Human molecular genetics 2005
Roberta Pietrobono Elisabetta Tabolacci Francesca Zalfa Ilaria Zito Alessandra Terracciano Umberto Moscato Claudia Bagni Ben Oostra Pietro Chiurazzi Giovanni Neri

The analysis of a lymphoblastoid cell line (5106), derived from a rare individual of normal intelligence with an unmethylated full mutation of the FMR1 gene, allowed us to reconstruct the chain of molecular events leading to the FMR1 inactivation and to fragile X syndrome. We found that lack of DNA methylation of the entire promoter region, including the expanded CGG repeat, correlates with met...

Journal: :Advanced Functional Materials 2022

Adv. Funct. Mater. 2020, 30, 1906013 DOI: 10.1002/adfm.201906013 In the original published article, one image in Figure 4C (PCL) and CT S3A (miR-5106) was reproduced incorrectly. The corrected figures are as follows. These errors do not affect conclusions of paper. authors apologize for any inconvenience these may have caused.

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