Background: Leber congenital amaurosis (LCA) is a rare inherited retinal disease causing severe visual impairment in infancy. It has been reported that 9-15% of LCA cases have mutations in CRB1 gene. The complex of CRB1 protein with other associated proteins affects the determination of cell polarity, orientation, and morphogenesis of photoreceptors. Here, we report three novel pathogenic varia...

background: this study assessed the relationship between working memory capacity and auditory stream segregation by using the concurrent minimum audible angle in children with a diagnosed auditory processing disorder (apd). methods: the participants in this cross-sectional, comparative study were 20 typically developing children and 15 children with a diagnosed apd (age, 9–11 years) according t...

extended abstract 1. introduction spatial segregation in tabriz metropolitan physically indicates some poor infrastructure indexes such as lack of arterial transportation networks, lack of water supply and sewage networks, inadequate housing, increasing and inhumane density, lack of service per capita, but from a social and cultural perspective, it is the vehicle of marginal identity that in in...

residential mobility is an important ecological mobility which, besides physical impacts, has contributed in shaping or reshaping of urban social milieus. the analyses of results related to a sample of 17510 households inhabiting in 40 regions of mashhad indicates that 46.9 percent of them had experienced a residential relocation during a period of ten years, the maximum of which (62.8 percent)...

Hybrid populations (F3) derived from cross between four moderate salt-resistant spring wheat (Triticum aestivum L.) were assessed for transgressive segregation of salt-tolerant genotypes allowing germination and emergence at 350 mM NaCl for 30 days. The achieved Selection intensity was the order of 0.24-0.27 in these segregation populations (22-25 seedlings from 9000 seeds). Assessment of trans...

objectives: this study investigated the efficacy of working memory training for improving working memory capacity and related auditory stream segregation in auditory processing disorders children. methods: fifteen subjects (9-11 years), clinically diagnosed with auditory processing disorder participated in this non-randomized case-controlled trial. working memory abilities and auditory stream s...