Anxiety disorders have become the number one mental health issue in developed countries. The of people living with anxiety and depressive rose significantly because COVID-19 pandemic. Although generally considered as safe effective, currently available anxiolytic therapy is responsible for numerous side effects addiction. Therefore, there an imperious demand discovering more efficient cheaper n...

One of the tasks pharmaceutical science is to find new sources effective drugs. Such include plants such as Angelica archangelica L. and sylvestris L., which have been used for many years treat various diseases in folk medicine. Because chemical composition these poorly understood, aim our study was investigate amino acid leaves A. The acids species genus were determined by HPLC method. Eightee...

Angelica archangelica (Fam. Apiaceae) roots were extracted sequentially with n-hexane, dichloromethane (DCM) and methanol (MeOH) using a Soxhlet apparatus. The n-hexane DCM extracts fractionated by Vacuum Liquid Chromatography (VLC) over silica gel followed Preparative Thin Layer (PTLC) to yield two coumarins, osthol (1) osthenol (2). However, the extract was solid-phase extraction C18 cartridg...