Naturally transmissible tumours can emerge when a tumour cell gains the ability to pass as an infectious allograft between individuals. The ability of these tumours to colonize a new host and to cross histocompatibility barriers contradicts our understanding of the vertebrate immune response to allografts. Two naturally occurring contagious cancers are currently active in the animal kingdom, ca...

the classification and imaging appearances of vascular masses of the head and neck are reviewed. the radiological appearances of congenital vascular masses (infantile haemangiomas and other congenital vascular tumours, high-flow and low-flow vascular malformations), acquired vascular masses (benign and malignant tumours, non-neoplastic lesions) and other hypervascular masses are described and i...

background : thymoma and thymic carcinoma are relatively rare tumours of the anterior mediastinum. optimum treatment options for these tumours remain unresolved, although at present, a multimodality approach involving aggressive surgical resection, platinum-based combination chemotherapeutic interventions and radiotherapy represents the preferred therapeutic approach. 1-3 this study evaluates t...

background: in the present study, the submandibularsalivary gland microscopic morphology of the adult africangiant pouched rat was investigated. this study was carried out toprovide the basic histology of this organ in the giant pouched rat,to accompany the dearth of information of its microscopicarchitecture in the available literature. this becomes of evenhigher importance when considering th...

OBJECTIVES The objective of this study was to identify an injection strategy leading to repeatable nanoparticle deposition patterns in tumours and to quantify volumetric heat generation rate distribution based on micro-CT Hounsfield unit (HU) in magnetic nanoparticle hyperthermia. METHODS In vivo animal experiments were performed on graft prostatic cancer (PC3) tumours in immunodeficient mice...

Regions of reduced oxygenation (hypoxia) are a characteristic feature virtually all animal and human solid tumours. Numerous preclinical studies, both in vitro vivo, have shown that decreasing oxygen concentration induces resistance to radiation. Importantly, hypoxia tumours is negative indicator radiotherapy outcome. Hypoxia also contributes other cancer therapeutics, including immunotherapy, ...

Many attempts have been made to produce immunity against cancer in animals. Bowdon in 1905 ligatured the vessels supplying the tumour and obtained necrosis of such growths but it had no effect on other tumours in the same animal. In 1906 Schone used injections of emulsions of normal fcetal and adult animal tissues without success. In 1908 Bashford, Murray and Cramer used injections of normal bl...