PURPOSE To assess the safety and efficacy of photorefractive keratectomy (PRK) in children with anisometropic amblyopia and to define the characteristics of children who may be candidates for PRK. METHODS This thesis comprises four parts: (1) a retrospective analysis of risk factors predictive of amblyopia treatment failure in 104 children, (2) a prospective study of pachymetry in 198 eyes of...

Introduction: Traditional therapy for anisometropic amblyopia often fails when severe anisometropia is present. Recent advances in refractive surgery for anisometropic amblyopia suggest that surgical treatment may be a viable alternative in certain situations. Methods: The potential indications for refractive surgery for anisometropia, the different refractive procedures available, and the risk...

PURPOSE It has previously been shown that anisometropic amblyopia affects the programming and execution of saccades. The aim of the current study was to investigate the impact of strabismic amblyopia on saccade performance. METHODS Fourteen adults with strabismic amblyopia, 13 adults with strabismus without amblyopia, and 14 visually normal adults performed saccades and reach-to-touch movemen...

Amblyopia is a neuro-developmental disorder of the visual cortex that arises from abnormal visual experience early in life. Amblyopia is clinically important because it is a major cause of vision loss in infants and young children. Amblyopia is also of basic interest because it reflects the neural impairment that occurs when normal visual development is disrupted. Amblyopia provides an ideal mo...

Several studies have indicated substantial processing deficits for static second-order stimuli in amblyopia. However, less is known about the perception of second-order moving gratings. To investigate this issue, we measured the contrast sensitivity for second-order (contrast-modulated) moving gratings in seven anisometropic amblyopes and ten normal controls. The measurements were performed wit...

PURPOSE Previous retrospective studies have found that integration of orientation information along contours defined by Gabor patches is abnormal in strabismic, but not in anisometropic, amblyopia. This study was conducted to reexamine the question of whether anisometropic amblyopes have contour integration deficits prospectively in an untreated sample, to isolate the effects of the disease fro...

Both visual acuity (VA) and contrast sensitivity (CS) are important parameters for measuring visual function. In this research, we investigated the CS of patients with ametropic or anisometropic amblyopia, whose corrected visual acuity (CVA) recovered to 1.0. Fifty-five cases with amblyopia and 22 control cases with a normal visual acuity of 1.0 were enrolled. The CS of the patients whose ametr...

IN the refraction clinic the visual improvement cannot always be correlated with the degree of anisometropia. The literature shows that anisometropic amblyopia is a well-recognized condition, but opinions differ regarding the relationship between anisometropia and amblyopia. As the published studies do not consider the factor of eccentric fixation as a possible variable, we have investigated it...

OBJECTIVE To find the causes of amblyopia in patients 4 to 14 years old attending out patient Ophthalmology department of Khyber teaching Hospital Peshawar. METHODS In this prospective cohort hospital based study 200 children aged 4-14 years were studied over a period of 12 months from December 2005 to November 2006 in outpatient department of Ophthalmology, Khyber Teaching Hospital. Visual a...

Background: We compared the wave amplitude of visually evoked potential (VEP) between patients with esotropic and anisometropic amblyopic eyes and a normal group.Methods: The wave amplitude of VEP was documented in 2 groups of persons with amblyopia (15 with esotropia and 28 with anisometropia) and 1 group of individuals with normal visual acuity (n, 15). The amplitude of P100 was recorded mono...