BACKGROUND The aim of this study was to assess the effect of an individualized GnRH antagonist regimen on folliculogenesis. METHODS In a multicentre, randomized, clinical trial, IVF/ICSI patients were allocated to a standard regimen, in which they received daily 0.25 mg GnRH antagonist ganirelix (Orgalutran) from the 6th day of stimulation onward (fixed regimen n = 102) or to an individualize...

Background The optimal stimulation protocol for poor responder patients is a therapeutic challenge. GnRH antagonist protocol has been proposed as a potentially proper option for poor responders. Nevertheless, there is no significant difference in terms of clinical pregnancy and cancellation rates be tween the GnRH antagonist and agonist cycles. Therefore, this subset of patients might be the be...

objective: coasting can reduce the ovarian hyperstimulation syndrome (ohss) risk in ovulation induction cycles before intracytoplasmic sperm injection (icsi). this study aimed to investigate the effect of gonadotropin-releasing hormone (gnrh) agonist and gnrh antagonist protocols to controlled ovarian hyperstimulation (coh) cycles with coasting on the parameters of icsi cycles and the outcome. ...

Resistance training (RT) improves the skeletal muscle’s ability to generate maximal voluntary force and is accompanied by changes in activation of antagonist muscle which not targeted primarily RT. However, nature role neural adaptation RT paradoxical well understood. We compared moments, agonist activation, agonist-antagonist coactivation, electromyographic (EMG) model-predicted moments genera...

In the present study, the effects of different doses of nicotine on immobility time in mice were tested. Intraperitioneal administration of low doses of nicotine (0.025 mg/kg) decreased, but higher doses (0.8 and 1 mg/kg) increased immobility time. The anti-immobility response induced by low doses of nicotine was inhibited by high doses of the D2 receptor antagonist sulpiride, the central nicot...

Cochinmicins I, II, III are novel peptolides produced in submerged-fermentation cultures of Microbispora sp. ATCC 55140. These closely related compounds are separated by HPLC and are novel competitive endothelin antagonists. Cochinmicins II and III are stereoisomeric to each other. Cochinmicin I is the deschloro analog of cochinmicin III.

te Amsterdam.

Background: Feeding behavior is regulated by a complex network which interacts via diverse signals from central and peripheral tissues. It is known dopaminergic and glutamatergic systems have crucial role on food intake regulation but scarce reports exist on their interaction in appetite regulation in broilers. OBJECTIVES: The present study was designed to examine the role of glutamatergic syst...