PURPOSE To evaluate agreement in central corneal thickness (CCT), keratometry, and anterior and posterior elevation map measurements in normal corneas between a combined Placido-Scheimpflug system and a combined Placido-scanning-slit elevation topography system. SETTING Department of Cataract & Refractive Surgery, Rothschild Foundation, Paris, France. DESIGN Evaluation of diagnostic test or...

BACKGROUND The aim of this study was to determine the correlation between corneal hysteresis (CH) and the corneal resistance factor (CRF), which are both novel methods of analyzing ocular rigidity/elasticity, and various corneal characteristics, mainly corneal volume in normal subjects. METHODS This cross-sectional study included 500 normal eyes of volunteers. An ocular response analyzer (ORA...

Purpose: To compare changes in posterior corneal elevation, anterior chamber depth (ACD), anterior chamber volume (ACV) and corneal volume (CV) after laser in situ keratomileusis (LASIK ) and photorefractive keratectomy (PRK) for low to moderate myopia by pentacam imaging Methods: In this prospective comparative case series, 105 consecutive myopic eyes randomly scheduled for LASIK (n=59) or PRK...

Purpose To investigate the biomechanical response of the cornea, lamina cribrosa (LC), and prelaminar tissue (PT) to an acute intraocular pressure (IOP) increase in patients with markedly asymmetrical glaucoma and in healthy controls. Patients and methods A total of 24 eyes of 12 patients with markedly asymmetrical primary open-angle glaucoma (POAG) and 12 eyes of 12 healthy patients were exa...

PURPOSE To determine the prevalence of keratoconus (KCN) and subclinical KCN among subjects with two or more diopters (D) of astigmatism, and to compare Pentacam parameters among these subjects. METHODS One hundred and twenty eight eyes of 64 subjects with astigmatism ≥2D were included in the study. All subjects underwent a complete ophthalmic examination which included refraction, visual acu...

PURPOSE To characterize the geometrical properties of keratoconic corneas upon intracorneal ring segments (ICRS) implantation, using custom-developed optical coherence tomography (OCT). METHODS Ten keratoconic corneas were measured pre- and post-ICRS surgery (7, 30, and 90 days). Corneal topographic and pachymetric maps were obtained from three-dimensional (3D) images acquired with OCT, provi...

PURPOSE To assess the agreement between the elevation and curvature measurements of the anterior and posterior corneal surfaces obtained using the Galilei Dual Scheimpflug Analyzer and those obtained using the Pentacam single Scheimpflug system. METHODS This prospective, noninterventional, diagnostic study was conducted at the Department of Ophthalmology at the American University of Beirut (...

During human embryogenesis, neural crest cells migrate to the anterior chamber of the eye and then differentiate into the inner layers of the cornea, the iridocorneal angle, and the anterior portion of the iris. When proper development does not occur, this causes iridocorneal angle dysgenesis and intraocular pressure (IOP) elevation, which ultimately results in developmental glaucoma. Here, we ...

PURPOSE To compare the keratometric and pachymetric parameters of healthy eyes with those affected by steep cornea and keratoconus (KC) using Scheimpflug camera. SETTING Briz-L Eye Clinic, Baku, Azerbaijan. DESIGN A cross-sectional study. METHODS In this study, 49 KC (Amsler-Krumeich stage 1) eyes and 36 healthy eyes were enrolled. A complete ophthalmic evaluation and a Scheimpflug camera...

PURPOSE The current and projected shortage of transplantable human donor corneas has prompted the development of long-term alternatives to human donor tissue for corneal replacement. The biosynthetic stromal substitutes (BSS) characterized herein represent a potentially safe alternative to donor organ transplantation for anterior corneal stromal diseases. The goal of this phase 1 safety study w...