A series of nine 2-arylidene-4-(4methoxy/phenoxy-phenyl)but-3-en-4-olides (I-IX) were screened against Pheretima posthuma earthworm species to assess the anthelmintic activity of the synthetic derivatives. The in vitro effects of compounds were evaluated at a concentration of 2mg/mL and time taken by the derivatives to paralyze and subsequently kill the worms was recorded. Synthetic butenolide ...

Suppressive anthelmintic treatment strategies originally designed to control Strongylus vulgaris in horses were extremely successful in reducing morbidity and mortality from parasitic disease. Unfortunately, this strategy has inadvertently resulted in the selection of drug-resistant cyathostomes (Cyathostominea), which are now considered the principal parasitic pathogens of horses. Resistance i...

The efficacy of essential oils of Cymbopogan nardus (citronella) and Azadirachta indica (neem) on Fasciola gigantica was assessed in vitro. The essential oil of citronella showed a potential anthelmintic activity whereas neem oil did not show any significant effect. Study revealed that 1% citronella oil showed anthelmintic effect on live Fasciola gigantica. The in vitro anthelmintic effect was ...

The Anthelmintic activities of different extracts of aerial parts of Cynodon dactylon Pers were evaluated separately on adult Indian earthworm (Pheritima posthuma). It was found that petroleum ether (PECD), chloroform (CECD), ethanol (EECD), aqueous extract (AECD) of C. dactylon showed anthelmintic activities at the concentration of 5 mg/ml of each. The anthelmintic effects of PECD, CECD, EECD ...

INTRODUCTION The problem of anthelmintic resistance in gastrointestinal nematodes (GIN) of small ruminants is world wide in distribution. In the past 20 years no new classes of anthelmintics have been developed for use in animals. Anthelmintic resistance has been documented to all classes of anthelmntics and multi-class resistance exists in many flocks. The challenge to veterinarians and produc...

Present study was carried out to investigate the anthelmintic potential of petroleum-ether extract of Portulaca oleracea against Pheretima posthuma as a species of earthworm. Various concentrations (25‐100 mg/ml) of petroleum-ether extract were evaluated for anthelmintic activity by recording the time required for paralysis and death of worms. Albendazole was used as standard. Result indicates ...

A survey to detect anthelmintic resistance in nematode parasites of sheep was conducted on 10 randomly-distributed farms in the Chivhu District, Mashonaland East Province, Zimbabwe. Before the survey, a questionnaire was circulated to the farmers concerning nematode parasite control. Results showed that parasite control using anthelmintic treatment was the only method practised and that the ben...

The apparent lack of anthelmintic resistant nematodes in cattle is due to the management systems used with most cattle and the lack of surveys for resistance. With extensive beef grazing or with beef suckler herds a large percentage of worms are in refugia (not exposed to anthelmintic) and few anthelmintic treatments are used. With dairy replacement heifers resistance can become a problem unles...

Parasitic worms modulate host immune responses in ways that affect microbial co-infections. For this reason, anthelmintic therapy may be a potent tool for indirectly controlling microbial pathogens. However, the population-level consequences of this type of intervention on co-infecting microbes are unknown. We evaluated the effects of anthelmintic treatment on bovine tuberculosis (BTB) acquisit...

There is a growing interest in traditional uses of plants for health care among different communities especially in the developing countries. Kashmir valley is a temperate agro-climatic zone of north-west temperate Himalayan region of India and is blessed with a diverse variety of medicinal flora. The traditional uses of plants against parasitic infections in human beings and their live-stock i...