A series of (28) 1-alkyl-3-methacryloyl (acryloyl)-benzimidazolone (thione) deriv-atives were synthesized. The structures of the new derivatives were confirmed by (1)H-NMR, (13)C-NMR and ESI-MS spectral analysis. The antibacterial activities of these compounds against several strains of bacteria, such as Bacillus cereus, Bacillus subtilis, Escherichia coli, Staphylococcus aureus and Pseudomonas...

Fatty acid methyl ester (FAME) extracts of four halophytic plants, viz. Arthrocnemum indicum, Salicornia brachiata, Suaeda maritima and Suaeda monoica belonging to the family Chenopodiaceae, were prepared and their composition was analyzed by GC-MS. The FAME extracts were also screened for antibacterial and antifungal activities. The GC-MS analysis revealed the presence of more saturated fatty ...

Our objective is to evaluate the antibacterial and antioxidant activity of ethanolic extracts of Plectranthus mollis (P.mollis) and Salvia officinalis (S. officinalis) leaves locally used for treatment of microbial infection in Nilgiris of India. Antibacterial activity was determined by using agar diffusion and broth dilution methods against seven microorganisms. The antioxidant potential was a...

Several,3-lactams were investigated on the affinity for the penicillin-binding proteins (PBPss) and the antibacterial activity in Bacillus subtilis. The 19-lactams uch as ampicillin, PS-5, methicillin and SCE-963, which had high affinities for PBP-2 showed strong antibacterial activities and the 3-lactams such as cephamycin C, Y-G19Z-GG and Y-G19Z-G, which had high affinities for PBP-1 but low ...

Citation: Lauritano C, Andersen JH, Hansen E, Albrigtsen M, Escalera L, Esposito F, Helland K, Hanssen KØ, Romano G and Ianora A (2016) Bioactivity Screening of Microalgae for Antioxidant, Anti-Inflammatory, Anticancer, Anti-Diabetes, and Antibacterial Activities. Front. Mar. Sci. 3:68. doi: 10.3389/fmars.2016.00068 Bioactivity Screening of Microalgae for Antioxidant, Anti-Inflammatory, Antican...

A series of new substituted benzophenone derivatives was designed, synthesized and screened for their antifungal and antibacterial activities. The bioassays indicated that most of the synthesized compounds showed some antifungal activity against the tested phytopathogenic fungi, but lower antibacterial activities towards the five vibrios isolated from marine sources. The preliminary structure a...

in the present study, we reported the essential oils chemical composition and antibacterial activities of the aerial parts of ajuga chamaecistus ging. ex benth. subsp. scoparia (boiss.) rech.f. thatwere collected duringmay 2013 and april 2014 and extracted by sde (simultaneous distillation–extraction) and clevenger apparatus. gc/ms analysis of the plant essential oils led to the identification ...

Silver(I)-induced instant gelation of pyridine-containing Fmoc-l-glutamate and its concentration-dependent self-assembly from nanotubes to nanofibers are investigated. The formed metallogel with nanostructure has remarkably enhanced antibacterial activities. Interestingly, the nanotube and nanofiber exhibit different antibacterial activities, and a corresponding antimicrobial mechanism is propo...

Novel pleuromutilin derivatives designed based on the structure of valnemulin were synthesized and evaluated for their in vitro antibacterial activities. These pleuromutilin derivatives with substituted amino moiety exhibited excellent activities against methicillin-resistant Staphylococcus aureus, methicillin-resistant Staphylococcus epidermidis, Escherichia coli, and Streptococcus agalactiae....

In medicinal chemistry nitrogen containing heterocycles are the most important compounds which show various biological activities. The cinnoline are nitrogenous derivatives and found to elicit many pharmacological actions like anti-hypertensive, antithrombotic, antihistamine, antileukemic, CNS activity, anti tumor, antibacterial and antisecretory activity. We planned to synthesis new series of ...