There has recently been much controversy surrounding the increased use of antibacterial substances in a wide range of consumer products and the possibility that, as with antibiotics, indiscriminate use of biocides might contribute to the overall pattern of susceptibility in the general environment and in the clinic. Such speculation, based on the isolation of resistant mutants from in vitro mon...

herbal medicinal products have attracted significant research interest in recent years. considering the efficiency of algae products in controlling pathogenic bacteria and also easy access to large resources of algae, this study was conducted to evaluate the effects of methanolic, chloroformic and aqueous extracts of gracilaria salicornia against aeromonas hydrophila , a heterotrophic, gram-neg...

Either the whole plant or plant products having medicinal properties are commonly known as medicinal plants. These medicinal plants are known to possess various phytochemicals, which exhibit more bioactivities such as antibacterial, antifungal, anticancer activity, etc. In this study, Aegle marmelos was collected from Chennai, crude extract of fruit and pulp of the chosen plant was subjected fo...

white spot lesions are observed in nearly 50% of patients undergoing orthodontic treatment. long-lasting antibacterial properties of orthodontic cements can reduce this phenomenon. the aim of this research was to compare antimicrobial activity of three commercial glass ionomer cements with three commercial zinc phosphate cements, over time, against streptococcus mutans and candida albicans. dir...

Recently, natural products have been evaluated as sources of antimicrobial agents with efficacies against a variety of microorganisms. This study described the antibacterial and antifungal activities of pomegranate peel extract (rind), seed extract, juice and whole fruit on the selected bacteria and fungi. The peel extract has shown highest antimicrobial activity compared to other extracts. Amo...

Applanoxidic acids and sterols, isolated from Ganoderma spp., were acetylated and/or methylated. The antibacterial activity against Escherichia coli and Staphylococcus aureus and the antifungal activity against Candida albicans and Trichophyton mentagrophytes of the derivatives were investigated by a microdilution method, and compared with those of the natural products. Both natural and modifie...

Respiratory and diarrheal diseases generate a substantial health burden globally and domestically, causing 7.0% and 3.5%, respectively, of all deaths worldwide each year (1). Among the infectious causes of death, lower respiratory tract infections rank first, causing an estimated 3.8 million deaths each year, and diarrheal diseases rank third, responsible for nearly 2 million deaths (1). The co...

We determined the prevalence of plasmid-mediated quinolone resistance mechanisms among non-Typhi Salmonella spp. isolated from humans, food animals, and retail meat in the United States in 2007. Six isolates collected from humans harbored aac(6')Ib-cr or a qnr gene. Most prevalent was qnrS1. No animal or retail meat isolates harbored a plasmid-mediated mechanism.

The pharmacokinetics of the quinolone enoxacin were studied after a 600-mg oral dose was given to each of six male volunteers. The levels of the compound were measured in serum, blister fluid, and urine. Absorption was variable, with peak levels (mean, 3.7 micrograms/ml) being attained between 0.75 and 3.0 h (mean, 1.9 h). The serum elimination half-life was 6.2 h, and 71.6% of the drug was rec...

Background and Objectives: There is a profound inclination among people toward consumption of herbs and herbal products. Some of these products are harmful while health-promoting potentials of some others should be discovered. In the present study the antibacterial, antioxidant, acute and subchronic and cancer cell toxicity of methanolic and aqueous extracts of Rosa damascena Mill. was