BACKGROUND & OBJECTIVES Antibiotic resistant bacterial nosocomial infections are a leading problem in intensive care units (ICU). Present investigation was undertaken to know antibiotic resistance in Acinetobacter baumannii and some other pathogens obtained from clinical samples from ICU causing nosocomial infections. Special emphasis was given on plasmid mediated transferable antibiotic resist...

The present study was aimed to detect the plasmid profile, the role of plasmid associated multiple antibiotic resistance of Vibrios isolated from coastal waters of Kerala. The isolated plasmids from antibiotic resistant Vibrios were tested for the presence of integrons using polymerase chain reaction (PCR) to elucidate the presence of plasmid borne integron, a key element in horizontal gene tra...

This study determined the plasmid profile and antibiotic resistance patterns of extended spectrum beta lactamases producing Pseudomonas aeruginosa expressing Amp C beta lactamase enzyme using standard procedures. Results obtained revealed that 32 (43.2%) had one plasmid, 37(50%) had two plasmids while the remaining five carried three plasmids each. The plasmid sizes ranged from 800bp to 25000-b...

Acinetobacter sp isolates deserve special attention once they have emerged globally in healthcare institutions because they display numerous intrinsic and acquired drug-resistance mechanisms. This study assessed the antibiotic susceptibility profile, the presence of the genetic marker blaOXA-23, and the clonal relationship among 34 nosocomial isolates of Acinetobacter spp obtained at a hospital...

Outer membrane proteins of Gram-negative bacteria play key roles in antibiotic resistance. However, it is unknown whether outer membrane proteins that respond to antibiotics behave in a specific manner. The present study specifically investigated the differentially expressed outer membrane proteins of an antibiotic-resistant bacterium, Edwardsiella tarda, a Gram-negative pathogen that can lead ...