BACKGROUND Several strategies to optimise the use of antibiotics have been developed. Most of these interventions can be classified as educational or restrictive. Restrictive measures are considered to be more effective, but the enforcement of these measures may be difficult and lead to conflicts with prescribers. Any intervention should be aimed at targets with the highest impact on antibiotic...

clindamycin is a lincosamide antibiotic which is approved for the treatment of anaerobic, streptococcal and staphylococcal infections. there has been an increased interest in the use of clindamycin since it achieves high intracellular levels in phagocytic cells, high levels in bone and appears to have an antitoxin effect against the toxin elaborating strains of streptococci and staphylococci. c...

competent to speak on hospitaf advances in Ulster without reference to this book; it should be in every doctor's library. It is an accurate unbiased survey of the first 75 years of this hospital when finances had to be found and fought for and when as yet the State had no control. Finally a book is often enhanced by its format, and Dr. Calwell is to be congratulated on the lay out and his choic...

Although the use of ‘magnifying glasses’ was recorded in the first century AD by Pliny the elder, the forerunner of the modern microscope was only developed in 1590 when a pair of Dutch spectacle makers, Zaccharias Jannsen and his son, discovered that pairing lenses allowed objects to be magnified. Galileo, on hearing of this discovery, experimented and outlined the science of lenses and produc...