Vinca rosea (fam. apocynaeceae) is a medicinal plant commonly grown in Indian gardens and a native of West Indies. Various parts of this plant have been reported to exert antidiabetic, hypotensive and antileukemic property (1-3). Significant hypoglycemic and antihyperglycemic activity of water soluble fraction of alcoholic extract of leaves of Vinca rosea in rats have already been reported by t...

background & aim: solenostemon monostachyus has remain invincible in ibibio ethnomedicine for the management of numerous ailment including diabetes mellitus. many of these ethnomedicinal claims are yet to be pharmacologically verified. the purpose of this study therefore was to subject the extract/fractions of solenostemon monostachyus used in folkloric management of diabetes to scientific ...


 Purpose: To investigate the in vitro antidiabetic, aphrodisiac and antimicrobial properties of para-propoxybenzoic acid isolated from Acacia auriculiformis stem bark.
 Methods: Powdered dried bark A. was extracted with 70 % ethanol water extract obtained suspended partitioned ethyl acetate n-butanol to give their respective soluble fractions. The fraction being more active, terms in...

Background. Nelumbo nucifera Gaertn. and Nymphaea lotus L. var. pubescens (Willd.) are both aquatic rhizomatous perennial plants mostly found in the tropical region of Nepal, India, Bangladesh, China, Eastern Asia. famous for their different biological activities such as antidiabetic, antioxidant, hepatoprotective, antidiarrheal, anti-inflammatory properties. Objective. The present study majorl...

BACKGROUND Natural extracts have played an important role in the prevention and treatment of diseases and are important sources for drug discovery. However, to be effectively used in these processes, natural extracts must be characterized through the identification of their active compounds and their modes of action. METHODOLOGY/PRINCIPAL FINDINGS From an initial set of 29,779 natural product...

OBJECTIVE To describe the use of oral antidiabetic drugs for management of type 2 diabetes in the U.S. from 1990 through 2001. RESEARCH DESIGN AND METHODS Data on oral antidiabetic drugs were derived from two pharmaceutical marketing databases from IMS Health, the National Prescription Audit Plus and the National Disease and Therapeutic Index. RESULTS In 1990, 23.4 million outpatient prescr...

BACKGROUND Insulin deficiency is the prime basis of all diabetic manifestations and agents that can bring about insulin secretion would be of pivotal significance for cure of diabetes. To test this hypothesis, we carried out bioactivity guided fractionation of Oreocnide integrifolia (Urticaceae); a folklore plant consumed for ameliorating diabetic symptoms using experimental models. METHODS W...