Introduction: Imidazole is an entity which is being synthesized in many of its derivative form from past few years; the entity is major source of interest for many of medicinal chemist to explore its various pharmacological potentials. In present article we review the chemistry of imidazole and its pharmacological actions as antihelmintics, anticancer, antifungal and anti-inflammatory agent by ...

A novel antifungal cyclic depsipeptide termed glomosporin, which has a fatty acyl side chain, was isolated from a barley solid culture of Glomospora sp. The strain was isolated from fallen pine leaves collected in Fukusima Prefecture, Japan and identified as Glomospora sp. BAUA 2825. Glomosporin was purified by butanol extraction followed by preparative HPLC. Glomosporin showed antimicrobial ac...

background: fungi may play a key part in periradicular diseases. the aim of this study was to evaluate and compare the antifungal properties of two root-end filling materials, proroot mineral trioxide aggregate (mta) and mta-angelus, against candida albicans using tube-dilution test. materials and methods: the antifungal properties of proroot mta and mta-angelus against c. albicans was assessed...

The isoxazolines have been reported to possess a variety of significant and diverse pharmacological activities such as antifungal (1, 2), anti-HIV (3), anti-bacterial (4), caspase inhibitory (5), antimuscarinic (6), anti-inflammatory (7), anticancer (8) and anti-depressant (9) activity. On the other hand, the object of antifungal drug discovery has become a subject of greater challenge due to i...

Introduction: Candida albicans is the most common oral fungus associated with oral candidial infections. Various antifungal agents are in use and the search is on for more agents showing anti candidial properties. Ganodermalucidum has been in use in Traditional Chinese Medicine for years. Literature supports the use of this Ganodermalucidum as a medicinal mushroom for its antimicrobial, antivir...

Natural dye extracted from aerial parts of Barleria prionitis and different kinds of textile fabrics dyed with the natural dye were investigated for their antifungal activity. Antifungal activity of natural dye and dyed fabrics was assessed against standard strains of five fungi namely Aspergillus flavus, A. niger, A. parasiticus, Fusarium moniliforme and Penicillium canescens using agar-we...

Purpose: Tissue conditioners are used for healing of abused oral tissues. They may harbour microorganisms causing oral diseases such as candidiasis compromising the health of the patient. Also, addition of antifungal agents into tissue conditioner may alter its properties. This study compares the anti-fungal property and mechanical properties of tissue conditioner containing different antifunga...