submitted after deadline Evaluation of anaesthetic activity of some aminoalkanol derivatives Tadeusz Librowski1, Anna M. Waszkielewicz2, Barbara Filipek1, Henryk Marona2 !! " #$% & ' !! " # % Derivatives of aminoalkanols such as KM113 and KM314 are considered anticonvulsant drug candidates, and they exhibit sodium channel blocking effect. Therefore, the aim of the study was to determine possibl...

creasing providing a rapidly expanding market for antiallergic drugs. The first generation anti-histamines penetrate the blood brain barrier and also possess anticholinergic properties and this has led to the development of a second generation of H1-antagonists such as terfenadine and astemizole. A common feature of first generation compounds includes two aryl or heteroaryl rings linked to an a...