How to cite this article: Govender T, Dawood A, Esterhuyse AJ, Katerere DR. Antimicrobial properties of the skin secretions of frogs. S Afr J Sci. 2012;108(5/6), Art. #795, 6 pages. http:// dx.doi.org/10.4102/sajs. v108i5/6.795 Antimicrobial resistance results in increased morbidity and mortality, and increased health-care costs. Therefore the need to develop new classes of antibiotics is indis...

Tuberculosis (TB) continues to be a devastating infectious disease and remerges as a global health emergency due to an alarming rise of antimicrobial resistance to its treatment. Despite of the serious effort that has been applied to develop effective antitubercular chemotherapies, the potential of antimicrobial peptides (AMPs) remains underexploited. A large amount of literature is now accessi...

PURPOSE Bacterial keratitis is an ocular infection with the potential to cause significant visual impairment. Increasing patterns of antibiotic resistance have necessitated the development of new antimicrobial agents for use in bacterial keratitis and other serious ocular infections. With a view to exploring the use of novel antimicrobial peptides in the management of ocular infection, we perfo...

Antimicrobial peptides have been isolated and characterized from tissues and organisms representing virtually every kingdom and phylum, ranging from prokaryotes to humans. Yet, recurrent structural and functional themes in mechanisms of action and resistance are observed among peptides of widely diverse source and composition. Biochemical distinctions among the peptides themselves, target versu...

Antimicrobial drug resistance is a major human health threat. Among the many attempts to tackle this problem, the synthesis of antimicrobial compounds that mimic natural antimicrobial peptides appears as a promising approach. Peptide-based dendrimers can be designed to have higher potency than natural antimicrobial peptides and at the same time they can evade the bacterial defense system. Novel...

background: lower respiratory tract infections (ltris) are among the most common infectious diseases with potential life-threatening complications. methods: the study consisted of 426 patients with suspected ltris from mid and far western region of nepal between september 2011 and july 2014. the specimens were collected and processed according to the standard microbiological methods at the cent...

background and aim: for rapid growing drug resistance among pathogenic microorganisms, it is essential to find new compounds with antimicrobial activity. medicinal herbs application in traditional treatment for thousand years, make this natural compound to the best choice for antimicrobial studies. the aim of this study is to determine the antimicrobial activity of artemisia against some import...