Antimony compounds are the cornerstone treatments for tegumentary leishmaniasis. The reactivation of herpes virus is a side effect described in few reports. We conducted an observational study to describe the incidence of herpes zoster reactivation during treatment with antimony compounds. The global incidence of herpes zoster is approximately 2.5 cases per 1,000 persons per month (or 30 cases ...

Plasmids in both Escherichia coli and Staphylococcus aureus contain an "operon" that confers resistance to arsenate, arsenite, and antimony(III) salts. The systems were always inducible. All three salts, arsenate, arsenite, and antimony(III), were inducers. Mutants and a cloned deoxyribonucleic acid fragment from plasmid pI258 in S. aureus have lost arsenate resistance but retained resistances ...

A novel fluorescent nanosensor for Sb(3+) determination was reported based on thioglycolic acid (TGA)-capped CdTe quantum dot (QD) nanoparticles. It was the first antimony ion sensor using QD nanoparticles in a receptor-fluorophore system. The water-soluable TGA-capped CdTe QDs were prepared through a hydrothermal route, NaHTe was used as the Te precursor for CdTe QDs synthesis. Bovine serum al...

Recently, Major R. N. Chopra, i.m.s., Pro| fessor of Pharmacology at the Calcutta School ; of Tropical Medicine, whilst carrying out some j pharmacological experiments with antimony ; compounds, noticed that when the serum from a kala-azar patient was added to certain of the pentavalent compounds of antimony a heavy precipitate was formed. He found that this precipitate was not formed if normal...

The selective retention of the Sb(III) chelate with ammonium pyrrolidine dithiocarbamate (APDC) on a column of Chromosorb 102 resin from a buffered sample solution including Sb(V) was used for the determination of Sb(III). The retained antimony was eluted with acetone. The retention of the Sb(III)-iodide compounds with sodium iodide on the Chromosorb 102 resin column from the same solution afte...

The gravimetric analysis of antimony(III) with oxine (8-quinolinol, Hox) was studied. The amount of antimony left in filtrate and washing solutions was corrected with the results of atomic absorption spectrometry. The weighing form, which had not been conclusive before the present study, was determined to be SbO(ox)(Hox)2. The result (purity of antimony(II) oxide: 99.84 +/- 0.05% (m/m)) of the ...

A sensitive atomic spectrometric method for the redox speciation analysis of antimony in soils is described. The method is based on the selective generation of stibine from Sb(III) in a continuous flow system using atomic fluorescence spectrometry for detection. Sb(V) is masked by citric or oxalic acid in HCl medium. The procedure was optimized with synthetic solutions of Sb(III) and Sb(V). The...

Elemental antimony occurs in the solid bulk in a metallic as well as an amorphous modification.[1] Over a wide temperature range the gas phase of elemental antimony comprises almost exclusively of tetrameric molecules;[2] however, a solid-state modification of antimony consisting of Sb4 molecules, comparable to white phosphorus and yellow arsenic, is not known to date. This is explained by the ...

In a previous paper of this series (1) we have shown that while the dilution curve for cod liver oil with antimony trichloride is not a linear function, a comparison can be made between the colorimetric assay of vitamin A in certain fish oils, with a chloroform solution of antimony trichloride, and the biological assay upon the same oils, when certain precautions are taken. In a second paper (2...

BACKGROUND Antimony resistance complicates the treatment of infections caused by the parasite Leishmania. METHODOLOGY/PRINCIPAL FINDINGS Using next generation sequencing, we sequenced the genome of four independent Leishmania guyanensis antimony-resistant (SbR) mutants and found different chromosomal alterations including aneuploidy, intrachromosomal gene amplification and gene deletion. A se...