Background: Synthetic azo dyes are very extensively using various industries such as food items and non-food items. Tartrazine is well known dye due to its wide range of applications, also acid yellow 23. Most release these containing effluents into water bodies without proper treatment. There no well-documented study about the toxicological effect tartrazine in fishes. studies with concentrate...

BACKGROUND This study was undertaken to investigation the effect of Diasulin, a poly herbal drug composed of ethanolic extract of ten medicinal plants on blood glucose, plasma insulin, tissue lipid profile, and lipidperoxidation in alloxan induced diabetes. METHODS Ethanolic extract of Diasulin a, poly herbal drug was administered orally (200 mg/kg body weight) for 30 days. The different dose...

Rats fed with alcohol (18%) at 3.76 g/day for 45 days showed significant reduction in body weight, glutathione (GSH) content and activities of superoxide dismutase (SOD) and catalase in liver. Lecithin cholesterol acyltransferase (LCAT) in plasma, levels of HDL cholesterol in serum, hepatic bile acid production and fecal excretion of neutral sterols also showed significant reduction. Simultaneo...

Butea monosperma popularly known as Flame of the Forest, Dhak, Palash or ‘Bastard teak’ which has immense potential and appears to have a broad spectrum of activity on several ailments. Previous phytochemical examination of this plant indicated the presence of various constituents some of these are Cajanin and isoformononetin; Stigmasterol; Butin; two known flavonoids, isobutrin (3, 4, 2', 4'-t...

The efficacy of melatonin (MLT) against ammonium acetate-induced neurotoxicity was biochemically studied in the experimental rats. The activities of serum transaminases and the levels of thiobarbituric acid reactive substances were significantly increased in ammonium acetate-treated rats. These levels were significantly decreased in MLT and ammonium acetate-treated rats. Further, non-enzymatic ...

The mechanism of propranolol-inhibited sarcolemmal membrane lipid peroxidation was investigated by electron spin resonance spin-trapping technique using 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) and 2-methyl-2-nitrosopropane (MNP). Highly purified canine myocytic sarcolemma were peroxidized by a superoxide-driven (from dihydroxyfumarate) and Fe3+-catalyzed free radical-generating system. Hydroxyl...

The protective mechanism of polyamines against acidified ethanol-induced gastric damage was studied. Their oral administration prevented the formation of gastric mucosal lesions induced by 90% ethanol in 150 mM HCl in a dose-dependent manner, with the order of the protective potency being spermine greater than spermidine greater than putrescine. The acidified ethanol-induced lesions were accomp...

The effects of pyrimido-pyrimidine derivatives (dipyridamole, RA-642 and mopydamole) on lipid peroxidation (inhibition of the production of malondialdehyde, MDA) in different regions of the rat brain were studied. Ferrous sulfate and ascorbic acid (FeAs) were used to induce lipid peroxidation via the formation of hydroxyl anions. The antiperoxidative effect of RA-642 (in the microM range) was 1...