A 57-year-old male was diagnosed with mycobacterium tuberculoma and was treated with isoniazid, rifampicin, ethambutol, and pyrazinamide. Three weeks after initiation of treatment, he presented with fever and appetite loss. Chest radiograph showed diffuse micronodular shadows on both lung fields. High-resolution chest computed tomography findings were diffuse parenchymal micronodules in both lu...

Intradural extramedullary tuberculoma of the spinal cord (IETSC) is an uncommon disease which can occurs secondary to tuberculous meningitis. A 31-year-old woman was diagnosed as tuberculous meningitis after mental disorientation. Her mentality was recovered after antituberculous therapy. After 7 months of antituberculous therapy, paraplegia has developed. Magnetic resonance imaging (MRI) revea...

Due to the risks of disease progression and transmission to the newborn, treatment of tuberculosis is often pursued during pregnancy and fixed-dose combined antituberculous agents have been found to be beneficial. Unfortunately, there is paucity of data on the safety of the fixed-dose combined antituberculous drugs during pregnancy. This study intends to assess the teratogenic effect of fixed-d...

Methods for measuring adherence to TB medication include detecting urine colour change due to the presence of rifampicin. However, this effect is short lived, peaking at 2–6 h and is only seen in ,50% of patients [2]. Directly observed therapy (DOT) will ensure adherence to antituberculous treatment, but this can be unacceptable and many patients do not tolerate a three times a week regimen. DO...

INTRODUCTION Tuberculous (TB) synovitis is a rare, treatable, potentially lethal form of extrapulmonary TB resulting from massive lymphohematogenous dissemination of Mycobacterium tuberculosis (M. tuberculosis). We presented a case of TB synovitis of the knee in a Caucasian HIV-negative man from Romania, a high TB incidence country. CASE REPORT A 65-year old man presented with cough, high fev...

The authors') studied previously on the in vitro combined effect of sulfisoxazole with antituberculous agents and reported that the effect consisted of the heterogeneous composition of bacterial population with regard to drug sensitivity and the retarding action of drugs on the generation time of the organism. This study concerned with the effect of sulfisoxazole with antituberculous agents inh...

introduction: acute leukemia covers a broad spectrum of hematological clonal diseases originating from the malignant transformation of stem cells. current chemotherapeutic methods result in an incomplete response to primary regimens in 30-40% of cases. methods: 20 patients who had been diagnosed with acute leukemia and who had displayed defined criteria in order to enter our study, were assesse...

Six patients with cerebral tuberculoma seen over a 2 year period are reported. Their clinical presentations, the result of investigations including radiological findings and their response to medical treatment are discussed and correlated with other reports in the literature. Eighty five percent of the patients were above the age of 30 years. All patients had negative past history of tuberculos...

BACKGROUND Tuberculosis is endemic in developing countries. However, calvarial tuberculosis is rare, even in areas where tuberculosis is endemic. In the literature, only few case series of calvarial tuberculosis have been reported. AIM To report a case series of 11 patients with calvarial tuberculosis, and discuss their presentation and management. MATERIALS AND METHODS This study is a retr...