OBJECTIVE/HYPOTHESIS Magnetic resonance imaging of the temporal bone has an important role in decision making with regard to cochlea implantation, especially in children with cochlear nerve deficiency. The purpose of this study was to evaluate the usefulness of the combination of an advanced high-resolution T2-weighted sequence with a surface coil in a 3-Tesla magnetic resonance imaging scanner...

Aplasia cutis and other scarring alopecias Congenital absence of skin (aplasia cutis) presents on the scalp as one or more noninflammatory well defined oval or circular ulcers, crusted areas (fig 1) or as scars. Lesions usually occur over the vertex in or adjacent to the midline and may involve skin only or occasionally may extend deeply to bone and dura. Complications include secondary infecti...

6. Peschle C, Marmont AM, Marone G, Genovesi A, Sasso G, Condorelli M: Pure red cell aplasia: Studies on an IgG serum inhibitor neutralizing erythropoietin. Br I Haematol 30:405, 1975 7. Krantz SB: Studies on red cell aplasia. III. Treatment with horse antihuman thymocyte gamma globulin. Blood 39:347, 1972 8. Marmont AM, Peschle C, Sanguineti M, Condorelli M: Pure red cell aplasia (PRCA): Respo...

An aplasia of the erythroblastic tissue in the bone marrow, without involvement of either leucocytes or platelets, is referred to by Whitby and Britton (1946) as a medical curiosity. This aplasia may be complete or partial. If complete, there is no formation of normal red-cell precursors. Strictly speaking, the term 'aplastic anaia ' should be reserved for cases of this kind, where there is a p...

Pure red-cell aplasia is an isolated disorder of erythropoiesis that leads to the pment of severe, isolated anemia. In chronic kidney disease patients treated with n erythropoiesis stimulating agent (ESA), development of anti-erythropoietin antibodies s one of the leading causes of pure red-cell aplasia. It requires to stop treatment with ESA, but in the vast majority of cases immunosuppressive...

The pathogenesis of diphenylhydantoin-induced pure red cell aplasia was investigated in the case of a 32-year-old man who developed pure red cell aplasia while he was under treatment with diphenylhydantoin. The patient’s serum lgG purified from serum drawn at the time of diagnosis suppressed normal allogeneic marrow colonyforming (CFU-E) and burst-forming (BFU-E) and autologous blood BFU-E grow...

Condylar aplasia which means "failure of development" is a rare condition and can be unilateral or bilateral. Mandibular condylar Aplasia without any association with syndrome is extremely rare. Temporomandibular joint (TMJ) ankylosis results from trauma, infection and inadequate surgical treatment of the condylar area. Congenital cases are very rare. We report case of congenital unilateral apl...

Admas-Oliver syndrome is a rare autosomal dominant disease of congenital development defects association with aplasia cutis. All of 81 reported cases were of 32 group families. These two cases had congenital scalp cutis aplasia with developmental defect and hypoplasia of left foot digits in case 1.Congenital deaf-mute in both can added to the past known findings in this syndrome. Thoracic defor...

Congenital torticollis is most commonly caused by sternomastoid contracture. Aplasia of sternomastoid muscle causing congenital torticollis, though rare, has been reported. However the association of cerebellar hypoplasia with sternomastoid aplasia is extremely rare. The authors describe a case of congenital torticollis due to absence of the left sternomastoid with ipsilateral cerebellar hypopl...

Salivary gland aplasia and hypoplasia are rarely described in the medical literature. This article presents a case of aplasia and hypoplasia of the major salivary glands in a patient with Down syndrome. A literature review, as well as an overview of the diagnosis and management of this condition, is presented.