BACKGROUND Sleep-disordered breathing is prevalent in the general population and has been linked to chronically elevated blood pressure in cross-sectional epidemiologic studies. We performed a prospective, population-based study of the association between objectively measured sleep-disordered breathing and hypertension (defined as a laboratory-measured blood pressure of at least 140/90 mm Hg or...

OBJECTIVE To explore the feasibility and efficacy of Z-palatoplasty for the management of severe obstructive sleep apnea-hypopnea syndrome in patients with tonsils. STUDY DESIGN Case series and chart review. SETTING University hospital. METHODS Z-palatoplasty and coblation channeling of the tongue were performed in 36 patients with body mass index <40 kg/m(2) and size 1 or 2 tonsils. All ...

Along with an increasingly sophisticated scientific approach to obstructive sleep apnea has come controversy over its true definition. By convention, the apnea– hypopnea index has been used to characterize obstructive sleep apnea. This index measures the frequency of reductions in airflow associated with upper-airway collapse or narrowing that occurs with the state change from wakefulness to sl...

OBJECTIVE To assess the relation between medications prescribed for chronic pain and sleep apnea. DESIGN An observational study of chronic pain patients on opioid therapy who received overnight polysomnographies. Generalized linear models determined whether a dose relation exists between methadone, nonmethadone opioids, and benzodiazepines and the indices measuring sleep apnea. SETTING A pr...

RATIONALE Although research supports a sleep-disordered breathing and atrial fibrillation association, prospective data examining sleep-disordered breathing predicting incident atrial fibrillation are lacking. OBJECTIVES To investigate sleep-disordered breathing indices as predictors of incident atrial fibrillation. METHODS A cohort (n = 843) of ambulatory older men without prevalent atrial...

INTRODUCTION Obstructive sleep apnea syndrome has a high prevalence among adults. Cephalometric variables can be a valuable method for evaluating patients with this syndrome. OBJECTIVE To correlate cephalometric data with the apnea-hypopnea sleep index. METHODS We performed a retrospective and cross-sectional study that analyzed the cephalometric data of patients followed in the Sleep Disor...

BACKGROUND As obesity increases, the frequency of obstructive sleep apnea and obesity hypoventilation syndrome increases also. However, obesity hypoventilation syndrome frequency is not known, as capnography and arterial blood gas analysis are not routinely performed in sleep laboratories. AIMS To investigate the frequency and predictors of obesity hypoventilation syndrome in obese subjects. ...

Obstructive sleep apnea (OSA) is characterized by episodes of pharyngeal collapse during sleep. Craniofacial alterations such as retrognathia are often found in OSA patients. Maxillomandibular advancement (MMA) surgeries increase the pharyngeal space and are a treatment option for OSA. The aim of this study was to present a successful case of MMA surgery in the treatment of OSA. A patient with ...

BACKGROUND Obstructive sleep apnea (OSA) is a major risk factor for perioperative adverse events. However, no screening tool for OSA has been validated in surgical patients. This study was conducted to develop and validate a concise and easy-to-use questionnaire for OSA screening in surgical patients. METHODS After hospital ethics approval, preoperative patients aged 18 yr or older and withou...

Sleep Apnea Syndrome (SAS) is a multimorbid chronic disease with individual and societal deleterious consequences. Polysomnography (PSG) the multi-parametric reference diagnostic tool that allows manual quantification of apnea-hypopnea index (AHI) to assess SAS severity. The burden affecting nearly one billion people worldwide explaining remains largely under-diagnosed undertreated. development...