OBJECTIVE Given that 30% to 40% of children have persistent obstructive sleep apnea (OSA) after adenotonsillectomy, we evaluated whether children with hypopnea-predominant OSA were more likely to have complete disease resolution after adenotonsillectomy than those with apnea-predominant disease. We also identified risk factors that might modify the relationship between disease resolution and po...

BACKGROUND The possible pathophysiology of the relationship between gastro-esophageal reflux disease and apnea of prematurity has been widely investigated. Various physiological protective reflex responses provide a plausible biological link between gastro-esophageal reflux and apnea of prematurity. It is uncertain whether or not there is a causal relationship between the two diseases. PATIENT'...

Prematüre apnesi, yenidoğan yoğun bakım ünitelerinde prematüre bebeklerde sıklıkla karşılaşılan bir durum olup, solunumun 15-20 sn'den daha fazla durması ya da kısa süreli solunum kesintisine oksijen satürasyon düşüklüğü ve/veya bradikardinin eşlik etmesi olarak tanımlanır. Gebelik haftası 28'in altında doğan bebeklerin hemen tümünde apne görülürken, gebelik büyüdükçe sıklığı azalmaktadır. doğu...

APNEA of prematurity and resultant intermittent hypoxic episodes are universal in preterm infants. These events range from presumably benign “periodic” breathing to clinically significant events that may require mechanical ventilation. Persistence of these events is a major factor in prolonging the hospitalization of preterm infants. Even though it is unclear whether this early instability of r...

BACKGROUND Methylxanthines reduce the frequency of apnea of prematurity and the need for mechanical ventilation during the first seven days of therapy. It is uncertain whether methylxanthines have other short- and long-term benefits or risks in infants with very low birth weight. METHODS We randomly assigned 2006 infants with birth weights of 500 to 1250 g during the first 10 days of life to ...

OBJECTIVE: To review medical literature related to apnea of prematurity. SOURCES: Extensive literature search and clinical practice-oriented concepts. SUMMARY OF THE FINDINGS: Apnea is one of the most common respiratory disorders in the neonatal period. Immaturity of the central nervous system is associated with instability of respiration. Therefore, apnea manifests itself in other systems, cau...

OBJECTIVE To compare the frequency and severity of apneic events in very low birth weight (VLBW) infants before and after blood transfusions using continuous electronic waveform analysis. STUDY DESIGN We continuously collected waveform, heart rate, and oxygen saturation data from patients in all 45 neonatal intensive care unit beds at the University of Virginia for 120 weeks. Central apneas w...

OBJECTIVE It is standard practice to defer discharge of premature infants until they have achieved a set number of days without experiencing apnea. The duration of this period, however, is highly variable across institutions, and there is scant literature on its effectiveness or value-for-money. Our objective was to establish the economic impact of varying durations of predischarge observation ...

We screened 50 neonates fulfilling the inclusion criteria admitted during the study period in a teaching hospital in a north-eastern state of India. Out of 50 neonates screened, 22 (44%) developed retinopathy of prematurity. There was significant association between the birth weight and gestational age of the baby at the time of the delivery with the development of ROP. Multivariate analysis of...