Background and Objective: Breast cancer patients need a variety of skills and abilities to deal with the consequences of the illness. Self-management is one of the operational strategies that leads to disease acceptance, treatment adherence, and improving the quality of life. The use of smartphone applications (apps) can play a pivotal role in the support and self-management of breast cancer pa...

for any reduced commutative $f$-ring with identity and bounded inversion, we show that a condition which is obviously necessary for the socle of the ring to coincide with the socle of its bounded part, is actually also sufficient. the condition is that every minimal ideal of the ring consist entirely of bounded elements. it is not too stringent, and is satisfied, for instance, by rings of conti...

for a fixed positive integer , we say a ring with identity is n-generalized right principally quasi-baer, if for any principal right ideal of , the right annihilator of is generated by an idempotent. this class of rings includes the right principally quasi-baer rings and hence all prime rings. a certain n-generalized principally quasi-baer subring of the matrix ring are studied, and connections...

this paper presents a genetic algorithm (ga) for solving a generalized model of single-item resource-constrained aggregate production planning (app) with linear cost functions. app belongs to a class of pro-duction planning problems in which there is a single production variable representing the total production of all products. we linearize a linear mixed-integer model of app subject to hiring...

background: we investigated the efficacy of a mobile-based  bolus advisor app in comparison with the usual multiple daily  injections (mdis) in diabetic patients. materials and methods: in a nonrandomized, controlled clinical trial, 62 diabetic patients  were selected to receive a 12-week intensive glycemic control by either a mobile-based bolus advisor (app) or mdi in the usual manner.we compa...

in atom transfer radical polymerization (atrp) of methyl acrylate (ma) with polyvinyl acetate macroinitiator in bulk at 90°c the plots of ln [m]0/[m] increased linearly with reaction time. the apparent propagation rate constant (kp app) of the reaction was obtained from the linear curve and used to calculate the free macroradical concentration ([r°]) in polymerization medium. the [r°] and also ...

APP-BP1, first identified as an amyloid precursor protein (APP) binding protein, is the regulatory subunit of the activating enzyme for the small ubiquitin-like protein NEDD8. We have shown that APP-BP1 drives the S- to M-phase transition in dividing cells, and causes apoptosis in neurons. We now demonstrate that APP-BP1 binds to the COOH-terminal 31 amino acids of APP (C31) and colocalizes wit...

Amyloid precursor protein binding protein-1 (APP-BP1) binds to the carboxyl terminus of the amyloid precursor protein (APP) and serves as the bipartite activation enzyme for the ubiquitin-like protein, NEDD8. In the present study, we explored the physiological role of APP-BP1 in the cell cycle progression of fetal neural stem cells. Our results show that cell cycle progression of the cells is a...

The processing of amyloid precursor protein (APP) to Abeta is an important event in the pathogenesis of Alzheimer's disease, but the physiological function of APP is not well understood. Our previous work has shown that APP processing and Abeta production are regulated by the extracellular matrix protein Reelin. In the present study, we examined whether Reelin interacts with APP, and the functi...