نتایج جستجو برای: aquaporin 1

تعداد نتایج: 2756237  

Journal: :Journal of pharmacological sciences 2004
Masato Yasui

The discovery of the water channel aquaporin has greatly expanded our understanding of the regulation of the water permeability of biological membranes. The atomic structure of aquaporin-1 (AQP1) demonstrated how aquaporin is freely permeated by water but not protons and provided marked insight into several human disorders. Eleven mammalian aquaporins have been identified, each with a distinct ...

Journal: :Archives of Sports Medicine 2020

2013
Umberto Laforenza Manuela F. Scaffino Giulia Gastaldi

BACKGROUND Glycerol outflow from adipocytes has been considered for a decade to be mediated by aquaporin-7, an aquaglyceroporin highly expressed in the adipose tissue. Its involvement in glycerol metabolism has been widely studied also in humans. Recent studies in different aquaporin-7 KO mice models pose two different questions 1) the exact localization of aquaporin-7 in human white adipose ti...

Journal: :The Journal of pharmacology and experimental therapeutics 2004
Prajakta A Sonalker Stevan P Tofovic Edwin K Jackson

The purpose of this study was to compare the expression of BSC-1 (bumetanide-sensitive Na+-K+-2Cl- cotransporter) in kidneys of spontaneously hypertensive rats (SHR) versus Wistar-Kyoto (WKY) rats by immunoblotting and reverse transcription-polymerase chain reaction. To determine the specificity of any observed changes in BSC-1 expression, we also compared expression of the thiazide sensitive N...

Journal: :Journal of Biological Chemistry 2004

2014
J.P. Fryer V.A. Lennon S.J. Pittock S.M. Jenkins P. Fallier-Becker S.L. Clardy E. Horta E.A. Jedynak C.F. Lucchinetti E.A. Shuster B.G. Weinshenker D.M. Wingerchuk A. McKeon

OBJECTIVE To compare performance of contemporary aquaporin-4-immunoglobulin (Ig) G assays in clinical service. METHODS Sera from neurologic patients (4 groups) and controls were tested initially by service ELISA (recombinant human aquaporin-4, M1 isoform) and then by cell-based fluorescence assays: fixed (CBA, M1-aquaporin-4, observer-scored) and live (fluorescence-activated cell sorting [FAC...

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