نتایج جستجو برای: arci
تعداد نتایج: 69 فیلتر نتایج به سال:
BACKGROUND Opioid analgesics can be abused by crushing followed by solubilization and intravenous injection to attain rapid absorption. Morphine sulfate and naltrexone hydrochloride extended release capsules (EMBEDA, MS-sNT), indicated for management of chronic, moderate to severe pain, contain pellets of morphine sulfate with a sequestered naltrexone core. Should product tampering by crushing ...
BACKGROUND Mutations in the gene encoding transglutaminase 1 (TG1) are responsible for various types of autosomal recessive congenital ichthyosis (ARCI), such as lamellar ichthyosis (LI), congenital ichthyosiform erythroderma (CIE) and some minor variants of ARCI. A point mutation of R143C in the β-sandwich domain of TG1 has been often identified in patients with LI or CIE. OBJECTIVE To eluci...
Hereditary ichthyoses are due to mutations on one or both alleles of more than 30 different genes, mainly expressed in the upper epidermis. Syndromic as well as nonsyndromic forms of ichthyosis exist. Irrespective of etiology, virtually all types of ichthyosis exhibit a defective epidermal barrier that constitutes the driving force for hyperkeratosis, skin scaling, and inflammation. In nonsyndr...
RATIONALE Eslicarbazepine acetate (ESL) is a once-daily oral antiepileptic drug for the treatment of partial-onset seizures. Adverse events such as dizziness and somnolence reported in clinical studies suggest that ESL has detectable central nervous system (CNS) effects in addition to its antiepileptic effects. This Phase I study evaluated the abuse liability of ESL compared with that of alpraz...
Pemoline, [(RS)-2-amino-5-phenyl-1,3-oxazol-4(5H)-one] is a central nervous system stimulant used to treat attention-deficit hyperactivity disorder (ADHD) and narcolepsy in humans (Molina and others 1981). In horse racing, pemoline is classified as an Association of Racing Commissioners International (ARCI) ‘Class 1’ foreign substance, i.e., an agent with high potential to influence performance...
The paper presents the results of research on citizenship competences civil service operators, carried out with participation Third Sector National Forum and Arci Civil Service. issue their enhancement is considered crucial both from policy level point view international studies. Eleven focus groups were conducted, aimed at volunteer distributed in ten different Italian regions, for a total 56 ...
A variety of neuropharmacological strategies are being pursued in the search for an effective treatment for methamphetamine (Meth) addiction. In this study, we investigated the safety and potential efficacy of aripiprazole, an antipsychotic agent acting on both dopamine and serotonin systems. We conducted a double-blind in-patient clinical pharmacology study to assess potential interactions bet...
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