Although arsenic trioxide (arsenite, As(III)) has shown a remarkable efficacy in the treatment of acute promyelocytic leukemia patients, multidrug resistance is still a major concern for its clinical use. Multidrug resistance-associated protein 4 (MRP4), which belongs to the ATP-binding cassette (ABC) superfamily of transporters, is localized to the basolateral membrane of hepatocytes and the a...

Arsenic (+3 oxidation state) methyltransferase (As3mt) catalyzes reactions which convert inorganic arsenic to methylated metabolites. This study determined whether the As3mt null genotype in the mouse modifies cytotoxic and proliferative effects seen in urinary bladders of wild type mice after exposure to inorganic arsenic. Female wild type C57BL/6 mice and As3mt KO mice were divided into 3 gro...

background facultative marine fungi could potentially be arsenic tolerant and may be able to remove this highly poisonous metal from the environment. objectives the objective of this work was to explore the degree of tolerance and removal efficiency of two facultative marine fungi. materials and methods facultative marine fungi aspergillus flavus and rhizopus spp. were exposed to 25 mg/l and 50...

Reference to this publication should be written as: Sandhi, A (2017) " Arsenic removal by phytofiltration and silicon treatment-A potential solution for lowering arsenic concentrations in food crops " TRITA-LWR PHD-2017:02 Arsenic phytofiltration and silicon application-lowering arsenic concentrations in food crops iii Dedicated to My Parents & the millions of people affected by arsenic contami...

Data on the mechanism of antimony genotoxicity is scarce. Arsenic and antimony are proposed to share some toxicological features. Thus comparative and combined experiments with As(III) and Sb(III) were performed to gain a deeper knowledge of the mechanism of antimony genotoxicity. Trivalent arsenic proved to be five times more cytotoxic and one order of magnitude more potent in induction of mic...

Schwertmannite, a kind of iron oxyhydrosulfate mineral, can removal arsenic(III) from arsenic(III)-bearing groundwater by the adsorption process. In this study, schwertmannite was bio-synthesized by Acidithiobacillus ferrooxidans LX5 in shaking flasks (160 rpm) containing a 0.16 mol/L FeSO4 liquid solution. After bio-synthesis, 25.5% of the bio-synthesized schwertmannite adhered to the reactor ...

A study on the removal of arsenic from real life groundwater using iron-chitosan composites is presented. Removal of arsenic(III) and arsenic(V) was studied through adsorption at pH 7.0 under equilibrium and dynamic conditions. The equilibrium data were fitted to Langmuir adsorption models and the various model parameters were evaluated. The monolayer adsorption capacity from the Langmuir model...

High levels of arsenic in groundwater and drinking water represent a major health problem worldwide. Drinking arsenic-contaminated groundwater is a likely cause of blackfoot disease (BFD) in Taiwan, but mechanisms controlling the mobilization of arsenic present at elevated concentrations within aquifers remain understudied. Microcosm experiments using sediments from arsenic contaminated shallow...

The bioaccumulation of arsenic by plants may provide a means of removing this element from contaminated soils and waters. However, to optimize this process it is important to understand the biological mechanisms involved. Using a combination of techniques, including x-ray absorption spectroscopy, we have established the biochemical fate of arsenic taken up by Indian mustard (Brassica juncea). A...

arsenic is one of the heavy metals and nearly all its compounds, especially organic compounds, are toxic. the wide spectrum of diseases caused by this element has led to evaluation of the toxicity of different arsenic species and identification of the major natural and anthropogenic pollution sources of it in the nature. mining activities are among the main sources of anthropogenic pollution of...