It has been proposed that the biological basis of autism spectrum disorder includes cerebellar 'disconnection'. However, direct in vivo evidence in support of this is lacking. Here, the microstructural integrity of cerebellar white matter in adults with Asperger syndrome was studied using diffusion tensor magnetic resonance tractography. Fifteen adults with Asperger syndrome and 16 age-IQ-gende...

Asperger Syndrome (AS) is a severe developmental disorder characterized by major difficulties in social interactio and restricted and unusual patterns of interest and behavior. There are many similarities with autism without retardation (or "Higher Functioning Autism"), and the issue of whether Asperger syndrome and Higher Functio Autism are different conditions is not resolved. To some extent,...

BACKGROUND During observation of the Necker cube perception becomes unstable and alternates repeatedly between a from-above-perspective ("fap") and a from-below-perspective ("fbp") interpretation. Both interpretations are physically equally plausible, however, observers usually show an a priori top-down bias in favor of the fap interpretation. Patients with Autism spectrum disorder are known to...

IMPORTANCE Prenatal folic acid supplements reduce the risk of neural tube defects in children, but it has not been determined whether they protect against other neurodevelopmental disorders. OBJECTIVE To examine the association between maternal use of prenatal folic acid supplements and subsequent risk of autism spectrum disorders (ASDs) (autistic disorder, Asperger syndrome, pervasive develo...

Autism and Asperger syndrome are diagnostic entities in a family of neurodevelopmental disorders disrupting fundamental processes of socialization, communication and learning, collectively known as pervasive developmental disorders. This group of conditions is among the most common developmental disorders, affecting 1 in every 200 or so individuals. They are also the most strongly genetically r...

Asperger syndrome is a pervasive developmental disorder on the higher-functioning end of the Autism Spectrum. Like many of the other Autism Spectrum Disorders (ASDs), people with Asperger‘s struggle in social situations and using social skills while executing everyday life activities. This is particularly notable during adolescence, when social skills and relationships gain complexity and behav...

The semantic and phonemic fluency performance of adults with high functioning autism (HFA), Asperger syndrome and a neurotypical control group were compared. All participants were matched for age and verbal ability. Results showed that the participants with HFA were significantly impaired in their performance of both semantic fluency tasks and the phonemic fluency task using the letter M. The A...

Theory of mind was assessed in 32 adults with HFA, 29 adults with Asperger syndrome and 32 neurotypical adults. The HFA and Asperger syndrome groups were impaired in performance of the Strange stories test and the Faux-pas test and reported more theory of mind problems than the neurotypical adults. The three groups did not differ in performance of the Eyes test. Furthermore, correlations betwee...

Esta investigación refiere algunas metodologías de enseñanza la matemática básica universitaria, en contextos los que se incluye personas estudiantes con síndrome Asperger. Se pretende orientar a docentes sobre cómo atender las necesidades educativas este escenario, identificar cuáles son limitaciones y indicadas, para asegurar una calidad. Este trabajo basa un estudio caso, donde analiza el co...