نتایج جستجو برای: asymmetric dimethylarginine

تعداد نتایج: 66105  

2017
You-Lin Tain Chien-Ning Hsu

Asymmetric and symmetric dimethylarginine (ADMA and SDMA, respectively) are toxic, non-proteinogenic amino acids formed by post-translational modification and are uremic toxins that inhibit nitric oxide (NO) production and play multifunctional roles in many human diseases. Both ADMA and SDMA have emerged as strong predictors of cardiovascular events and death in a range of illnesses. Major prog...

Journal: :The Journal of biological chemistry 2012
Cecilia I Zurita-Lopez Troy Sandberg Ryan Kelly Steven G Clarke

Full-length human protein arginine methyltransferase 7 (PRMT7) expressed as a fusion protein in Escherichia coli was initially found to generate only ω-N(G)-monomethylated arginine residues in small peptides, suggesting that it is a type III enzyme. A later study, however, characterized fusion proteins of PRMT7 expressed in bacterial and mammalian cells as a type II/type I enzyme, capable of pr...

Journal: :Journal of the Formosan Medical Association 2011

Journal: :American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2010

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