Aim of the present investigation was to analyse the possible malignant transformation of oral lichen planus to carcinoma, especially in the atrophic erosive forms and those displaying plaques involving the top of the tongue. A review has been made of the literature, from 1986 to the present day. This search outlines the relationship between oral lichen planus, hepatitis C virus infection, Epste...

introduction:oral lichen planus(olp)is a chronic mucocutaneus disease with an immunological etiology. this study was conducted to evaluate the effect of cedar honey in treatment of erosive- atrophic olp.materials and methods: thirty patients with confirmed clinical and histopathologic of olp participated in a randomized clinical trial in mashhad dental school.patients were randomly allocated in...

Xeroderma pigmentosum (XP) is a rare genetic disease characterised by defective DNA repair leading to clinical and cellular hypersensitivity to ultraviolet radiation. The oculocutaneous features of 10 patients with XP were studied retrospectively. General features included parental consanguinity (40%), familiarity (60%), onset of symptoms in first 2 years (50%), malignant skin neoplasms (60%), ...

We describe a 14-year-old female patient with progressive ponto-bulbar palsy and deafness. The first symptom was present at the age of 9 as a difficulty in walking and then she was stable with mild clumsy walking till 14 year-old. It was noticed that she had rapidly progression gait disorder, hearing loss, difficulty in swallowing and speaking in a period of 2.5 months. Clinically, there were b...

INTRODUCTION We present the case of a patient with a cobalamin deficiency resulting in pancytopaenia, emphasizing the importance to define, diagnose and treat cobalamin deficiency. CASE PRESENTATION A 52-year-old man from the Democratic Republic of Congo presented to the emergency department with shortness of breath and a sore tongue. Physical examination was unremarkable. His haemoglobin was...

OBJECTIVE The aim of this study was to determine the prevalence of dental and oral mucosal lesions in institutionalised elderly people in Rasht. BACKGROUND Oral health in the elderly people is important to tailor the health programmes for this increasing age group within the population. METHODS A total of 216 elderly people residing in a geriatric nursing home were included in the study. Su...

background: currently, non-invasive methods for screening atrophic gastritis and gastric cancer are lacking. the purpose of this study was to evaluate the value of serological parameters including serum pepsinogen i (pgi), pepsinogen ii (pgii) and pepsinogen i: ii ratio for the screening atrophic gastritis and gastric cancer.   methods : the study population consisted of 132 dyspeptic patients ...

objectives: geographic tongue or migratory glossitis is an inflammatory disorder with unknown etiology. considering the accompanied burning pain, taste dysfunction, and lack of definite cure, it is important to treat this condition symptomatically. the objective of the current study was to compare the efficacy of a combination of 0.05% retinoic acid and 0.1% triamcinolone acetonide with that of...

OBJECTIVE Vaginal atrophy in menopause shows increased parabasal cells on cytology. This may be accompanied by abundant neutrophils. A shift in maturation index in the absence of significant inflammation is more accurately termed "atrophic pattern." This study aims to determine whether a diagnosis of "atrophic vaginitis" or atrophic pattern on Papanicolaou test is a reliable indicator of what i...