introduction: the incidence of multidrug resistant tuberculosis is increasing in developing countries. aminoglycosides are an integral part of second-line drugs, however ototoxicity is a major limitation for their use. this study aims to determine the extent of hearing loss in patients taking one of the commonly prescribed drugs for multidrug resistant tuberculosis (mdr-tb), kanamycin, at a gov...

This study aimed to evaluate audiological and vestibular involvement in Fabry disease and the effects of enzyme replacement therapy with human α-galactosidase A. The study population comprised 20 patients (11 males, 9 females) aged 15-69 years (mean 39.7). Patients underwent a complete clinical and instrumental evaluation before starting and during enzyme replacement therapy. median follow-up w...

OBJECTIVES To determine (1) detailed retinal and audiological features of probands harboring the A3243G mitochondrial DNA mutation (m.3243A>G) and their asymptomatic maternal relatives, (2) intrafamilial and interfamilial phenotypic variability, and (3) the presence of other systemic features. METHODS Seven probands harboring the A3243G mitochondrial DNA mutation and 36 asymptomatic maternal ...

UNLABELLED The accuracy of parents' impressions about their child's hearing status is variable and may not correspond to the child's complaints. AIM To investigate children's self-reported hearing symptoms and parents' impressions about it. METHODS 477 children (2nd to 5th grades of elementary schools) were interviewed and parents answered a survey at home. There were 393 matches between th...

Background/aim: Fibromyalgia (FM) patients may have several neuroendocrine dysfunctions, resulting in a hypervigilant sensory output that may be responsible for sensorineural complaints. In this study, we evaluated the audiological findings of a cohort of female fibromyalgia patients. Materials and methods: Between 1 September 2012 and 1 June 2013, 35 female FM patients, followed by the Departm...

UNLABELLED Noise-induced hearing loss has been studied for many years and today many experts also investigate the synergic action of chemical products, since they can be potentially ototoxic. AIM to investigate the audiological findings in workers exposed to occupational noise and pesticide and to compare it to data from noise-exposed workers. STUDY DESIGN Clinical retrospective. MATERIAL...

UNLABELLED Frontonasal dysplasia (FND) is a rare malformative complex affecting the frontal portion of the face, the eyes and the nose; it may occur singly or associated with other clinical signs. No systematic studies describing hearing in this condition were found. AIM To evaluate hearing sensitivity and sound stimulus conduction from cochlea to brainstem in patients with clinical signs of ...