Stewart LT. Cell adhesion proteins and the pathogenesis of autism spectrum disorders. J Neurophysiol 113: 1283–1286, 2015. First published July 2, 2014; doi:10.1152/jn.00780.2013.—Current theories on the pathogenesis of autism spectrum disorders (ASD) maintain that the associated cognitive and behavioral symptoms are caused by aberrant synaptic transmission affecting specific brain circuits. Tr...

the autism spectrum disorders (asd) are amongst the most heritable complex disorders. although there have been many efforts to locate the genes associated with asd risk, many has been remained to be disclosed about the genetics of asd. scrutiny's have only disclosed a small number of de novo and inherited variants significantly associated with susceptibility to asd. these only comprise a s...

Autism spectrum disorder (ASD) is a group of complex neurodevelopmental disorders whose diagnosis exclusively made on behavioral basis. According to the diagnostic and statistical manual mental disorders, autism defined by deficits in two main symptoms (social interaction & communication, repetitive/restrictive behaviors), which emerge premature phases postnatal development. The authors rev...

the aim of the present study was to compare the broader autism phenotype in iranian parents of children with autism spectrum disorders and parents of typically developing children.parents of children with asd and parents of typically developing children were asked to complete the persian version of the autism spectrum quotient (aq). in the asd group, families included 204 parents (96 fathers an...

autism spectrum disorder (asd) is a mental condition, present from early childhood, characterized by great difficulty in communicating and forming relationships with others and using language. in the last four decades many studies have shown that immune responses in different regions of brain play an important role in asd pathogenicity. a conservative estimate based on the research suggests tha...

Face recognition refers to an individual's understanding and interpretation of the human face especially in relation to the associated information processing in the brain. Autism Spectrum Disorder (ASD) is a comprehensive neural developmental disorder that produces many deficits including social, communicative and perceptual. Individuals with autism exhibit difficulties in various aspects of fa...

KDM5B, a histone lysine demethylase “eraser” protein, is transcriptional repressor of active promoter regions on 3 K4. KDM5B crucial to regulating gene expression and development. Previously, all mutations in were described cancer. High-performance sequencing revealed missense, frameshift, nonsense that can be linked developmental disorders like autism spectrum disorder (ASD). This review summa...

Inflammatory reaction and asthma in certain children with features of autism spectrum disorders (ASD) as well attention-deficit hyperactivity disorder (ADHD) have been reported previously.