Introduction:Guillain-Barre Syndrome(GBS) is the most common cause of acute flaccid paralysis. Respiratory failure is the most serious short-term complication of GBS and invasive mechanical ventilation is required in 30% of patients.moreover,60% of those who are intubated develop major complications including pnemonia,sepsis,GI bleeding and pulmonary embolism. Thus respiratory failure predictio...

BACKGROUND Local anesthetics that produce analgesia of long duration with minimal impairment of autonomic functions are highly desirable for pain management in the clinic. Prenylamine is a known calcium channel blocker, but its local anesthetic blocking effects on voltage-gated sodium channels have not been studied thus far. METHODS The authors characterized the tonic and use-dependent prenyl...

Postherpetic neuralgia (PHN) is a common and exceptionally drug-resistant neuropathic pain condition. In this cross-sectional skin biopsy study, seeking information on the responsible pathophysiological mechanisms we assessed how ophthalmic PHN affects sensory and autonomic skin innervation. We took 2-mm supraorbital punch skin biopsies from the affected and unaffected sides in 10 patients with...

background many multimodal analgesia techniques have been tried to provide adequate analgesia for midline incisions extending above and below the umbilicus aiming at limiting the perioperative use of morphine thus limiting side effects. ultrasound (us) guidance made the anesthesiologist reconsider old techniques for wider clinical use. the rectus sheath block (rsb) is a useful technique under-u...

results totally, 20 patients completed the study. the cms and pain scores significantly improved after the block. conclusions the use of the modified lateral ssnb of feigl significantly reduces pain and increases shoulder function, in chronic shoulder pain. patients and methods patients were evaluated using the constant-murley score (cms) and number rating scale values for pain. the ssn was blo...

OBJECTIVE To determine the effects of topical application of capsaicin on cutaneous autonomic nerves. METHODS Thirty-two healthy subjects underwent occlusive application of 0.1% capsaicin cream (or placebo) for 48 hours. Subjects were followed for 6 months with serial assessments of sudomotor, vasomotor, pilomotor, and sensory function with simultaneous assessment of innervation through skin ...

Diabetic polyneuropathy is a specific form of peripheral nerve disorder, in which distal nerve axons degenerate insidiously under hyperglycemia of diabetes mellitus. Although all types of peripheral nerve fibers are involved, it is usually sensory dominant with eventual involvement of autonomic and motor nerve fibers. Its manifestation ranges from subclinical changes in nerve conduction to pain...

introduction: pain control is the most important issue in emergency department management of patients with femoral bone fractures. the present study aimed to compare the procedural features of ultrasonography and nerve stimulator guided femoral nerve block in this regard. method: in this randomized clinical trial, patients with proximal femoral fractures presenting to emergency department were ...

Experiments were performed on open-chest anesthetized dogs to determine the quantitative effects of autonomic nerve stimulition or pacemaker activity and conduction. The lead II electrocardiogram together with bipolar electrograms were recorded from the atria, the His bundles, and the ventricles. The vagi or the stellate gangba were stimulated in dogs which exhibited either sinus rhythm, ectopi...