A negative sentinel lymph node (SLN) biopsy spares many breast cancer patients the complications associated with lymph node irradiation or additional surgery. However, patients at high risk for nodal involvement based on clinical characteristics may remain at unacceptably high risk of axillary disease even after a negative SLN biopsy result. A Bayesian nomogram was designed to combine the proba...

BACKGROUND Sentinel node biopsy predicts accurate pathological nodal staging. The survival of node-negative breast cancer patients should be evaluated between the patients treated with sentinel node biopsy alone and those treated with axillary lymph node dissection. METHODS Ninety-seven patients with negative axillary nodes underwent sentinel node biopsy immediately followed by axillary lymph...

background : the axillary lymph node stage is one of the single most important determinants in the prognosis of breast cancer patients. the disadvantages of the two previous methods used for evaluating axillary node metastasis, i.e., axillary lymph node dissection and sentinel lymph node biopsy, have directed researchers to investigate new techniques for this purpose. the aim of the current stu...

background: sentinel lymph node biopsy (slnb) has replaced axillary lymph node dissection (alnd) in early breast cancer patients as the first line surgical approach to axillary nodes. further dissection is performed only when sln is involved by tumor cells. however, in a significant proportion of patients, non-sentinel nodes are still not involved and axillary dissection has no additional thera...

AIM The aim of this study was to determine factors that predict non-sentinel axillary lymph nodes (NSLNs) metastases in breast cancer patients with positive sentinel node biopsy (SLNB). MATERIAL OF STUDY We reviewed the records of a consecutive series of 176 breast cancer patients who underwent SLNB at our institution. From the database we analysed those cases with one or more positive sentin...

During the study period, 194 cases of breast cancer were identified on screening mammography in 40-49 year old women; 53% invasive cancer and 47% ductal carcinoma in situ. Of the patients with invasive disease, 23% had axillary nodal involvement. A very strong family history was absent in 90%, and extremely dense breast tissue was absent in 86%. 78% patients had neither very strong family histo...

background: primary leiomyosarcoma (lms) of the breast is a very rare neoplasm of the breast arising from the mesenchymal tissue. the clinical presentation of this entity simulates other benign and malignant lesions of mesenchymal tissue of the breast. case presentation: case 1: a 40-year-old female presented with a right-sided breast lump, which was suspected to be a malignant spindle cell tum...

background: the aim of this study was to detect prognostic factors in recurrent breast cancer metastasis. materials and methods: th is retrospective cohort study employed data from 996 breast cancer patients of isfahan seyed-o-shohada research center from 1998 to 2010. stratifi ed cox proportional hazards model, marginal approach, was used to evaluate the prognostic value of estrogen receptor, ...

AIM To assess the diagnostic value of pre-surgery axillary ultrasound for nodal staging in patients with primary breast cancer and to identify clinical/histopathological factors impacting diagnostic performance. STUDY DESIGN Single-center, retrospective chart analysis. We assessed sensitivity, specificity, and positive and negative predictive value of clinical examination as well as axillary ...