IMPORTANCE Recent data from clinical trials have challenged traditional thinking about axillary surgery in patients with breast cancer. OBJECTIVES To summarize evidence regarding the role of axillary interventions (surgical and nonsurgical) in breast cancer treatment and to review the association of these axillary interventions with recurrence of axillary node metastases, mortality, and morbi...

Introduction: One of the major problems of lymphoscintigraphy is the time of patient presence in the nuclear medicine wards. The operating room schedule can be compromised if the patients stay longer than usual in the nuclear medicine departments. However, too early imaging can be falsely negative for sentinel node visualization and delayed imaging may be required. The aim of t...

BACKGROUND Breast cancer is one of the most commonly occurring malignancies in females in the Eastern Mediterranean Region. Axillary clearance is an integral part of the surgical treatment of breast cancer. Precise analysis of lymph node involvement for proper staging and adjuvant therapy is therefore necessary. During axillary dissection, lymph nodes at levels I, II and III are removed, while ...

Objective: To provide information needed by patients with breast cancer (stages I and II) and their physicians when deciding whether axillary dissection should be carried out. Options: No axillary surgery; removal of all axillary lymph nodes; removal of level 1 and 2 nodes; axillary “sampling.” Outcomes: Accurate determination of stage of cancer, resulting in better-informed therapeutic decisio...

BACKGROUND While lymph node metastasis is among the strongest predictors of disease-free and overall survival for patients with breast cancer, the immunological nature of tumor-draining lymph nodes is often ignored, and may provide additional prognostic information on clinical outcome. METHODS AND FINDINGS We performed immunohistochemical analysis of 47 sentinel and 104 axillary (nonsentinel)...

510 cases of surgical lymph node biopsies during a five year periode are reviewed with the following conclusionsthe lymph node biopsy constitues 5% of all the surgical biopsies, the cervical and axillary lymph nodes are the most commonly biopsicd nodes due to their easy accessibility and due to the fact that they drain the lymph from many vital organs: the next most commonly biopsied nodes are ...

AIM The aim of the study was to identify the impact of T stage, the presence of estrogen, progesterone, HER2neu receptors and the values of the Ki67 on the positivity for metastases of the axillary lymph nodes, from primary breast cancer. MATERIAL AND METHODS 290 surgically treated patients for breast cancer were included in the study. All cases have been analyzed by standard histological ana...

Background: To explore a possible rela!onship among blood groups and the prognosis of breast cancer, this case- control study was carried out in Arak city, Arak province, Iran. Materials and Methods: One hundred and thirty four pa!ents with breast cancer were inves!gated. ABO blood groups were obtained from medical records. Mul!variate analyses were performed, including size of tumor, axilla...

BACKGROUND After completion of axillary dissection, many breast cancer patients with axillary sentinel nodal involvement are found to have regional disease limited to the sentinel nodes. These patients are exposed to the morbidity of axillary clearance without any expected therapeutic benefit. METHODS Sentinel node biopsy was performed either with Patent blue dye or with a combined dye, radio...