Structural diversification of canonical nucleic acid bases and nucleotide analogues by tautomerism has been proposed to be a powerful on/off switching mechanism allowing regulation of many biological processes mediated by RNA enzymes and aptamers. Despite the suspected biological importance of tautomerism, attempts to observe minor tautomeric forms in nucleic acid or hybrid nucleic acid-ligand ...

A novel of Chemosensor compound 4-((E)-(2-(2,4-dinitrophenyl) hydrazineylidene) methyl)-2-methoxy-6-((E)-phenyldiazenyl)phenol has designed and synthesized from 2,4-dinitrophenyl hydrazine (E)-4-hydroxy-3-methoxy-5-(phenyldiazenyl)benzaldehyde. This sensor was applied as a colorimetric for recognition cyanide anion in acetonitrile solution. In the presence ion, solution turned bright yellow to ...

–A novel series of 2-phenyl-5-sulpha/substituted-3-phenyl substituted azo indoles have been synthesized and tested as an antifertility activity in mature albino mice. The tested compounds showed significant antifertility activity. Keywords––Synthesis, Antifertility activity, Indore, Azo indoles, chemical analysis.

The unprecedented diaza-ene reaction of formaldehyde N-tert-butyl hydrazone with nitroalkenes can be efficiently catalyzed by an axially chiral bis-thiourea to afford the corresponding diazenes in good to excellent yields (60-96%) and moderate enantioselectivities, up to 84 : 16 er; additional transformation of diazenes into their tautomeric hydrazones proved to be operationally simple and high...

A compound exhibits (prototropic) tautomerism if it can be represented by two or more structures that are related by a formal intramolecular movement of a hydrogen atom from one heavy atom position to another. When the movement of the proton is accompanied by the opening or closing of a ring it is called ring-chain tautomerism. This type of tautomerism is well observed in carbohydrates, but it ...