Bacillus Calmette-Guérin (BCG) is a vaccine used to prevent tuberculosis. It made from live, attenuated strain of Mycobacterium bovis . When injected into the human body, it causes mild infection that produces immunity tuberculosis bacterium. The BCG primarily as preventive measure against in children, and generates special resistance disease. To honor its inventors, French scientists Ca...

Rates of tumor cell loss, replication, and growth were determined simultaneously for P-815 mastocytoma cells placed in culture or transplanted as a peritoneal ascites tumor. Cytokinetic parameters were concordant in vitro to in vivo for P-815 cells growing in the presence of syngeneic DBA/2 resident or proteose peptone-elicited macrophages and under allogeneic C57BL/6 nonimmune conditions. Unde...

et al. Incidence and treatment of complications of bacillus Calmette-Guerı́n intravesical therapy in superficial bladder cancer. J Urol. 1992;147:596–600. 6. Van der Meijden AP, Sylvester RJ, Oosterlinck W, Hoeltl W, Bono AV. Maintenance Bacillus Calmette-Guerin for Ta T1 bladder tumors is not associated with increased toxicity: Results from a European Organisation for Research and Treatment of ...

OBJECTIVE To evaluate the multiphase contrast-enhanced magnetic resonance (MR) imaging features of Bacillus Calmette-Guérin (BCG)-induced granulomatous prostatitis (GP). MATERIALS AND METHODS Magnetic resonance images obtained from five patients with histopathologically proven BCG-induced GP were retrospectively analyzed for tumor location, size, signal intensity on T2-weighted images (T2WI) ...

NOD2/CARD15 mediates innate immune responses to mycobacterial infection. However, its role in the regulation of adaptive immunity has remained unknown. In this study, we examined host defense, T cell responses, and tissue pathology in two models of pulmonary mycobacterial infection, using wild-type and Nod2-deficient mice. During the early phase of aerosol infection with Mycobacterium tuberculo...

When cultured in vitro, peritoneal macrophages, obtained from mice previously inoculated with bacillus Calmette-Guérin, release nitric oxide, which is cytostatic and/or cytolytic for tumor cells. However, it is not known whether nitric oxide has antitumor effects in vivo. Here we demonstrate that nitric oxide is an important mediator of host resistance to syngeneic and xenogeneic ovarian tumor ...