AIM To report an increased incidence of sterile endophthalmitis following intravitreal injection of preserved triamcinolone acetonide (IVTA) from 1 May to 31 July 2006. METHODS Charts were reviewed for all patients who underwent IVTA injections between 1 January 2005 and 31 July 2006 at the offices of a referral vitreo-retinal practice. Patients were included if they presented post-IVTA with ...

BACKGROUND Activation of innate immunity plays a key role in determining the outcome of an infection. Here, we investigated whether Toll-like receptors (TLRs) are involved in retinal innate response and explored the prophylactic use of TLR2 ligand in preventing bacterial endophthalmitis. METHODS C57BL/6 mice were given intravitreal injections of Pam3Cys, a synthetic ligand of TLR2, or vehicle...

OBJECTIVES To determine the rate of endophthalmitis in a group of patients with keratoprostheses and to analyze possible risk factors. METHODS A total of 108 patient eyes, operated on between 1990 and 2000 with double-plated keratoprostheses, were analyzed with regard to the surface flora, the incidence and cause of bacterial endophthalmitis or sterile vitreitis, the keratoprosthesis design, ...

PURPOSE To determine the influence of topical vancomycin prophylaxis on the incidence of bacterial endophthalmitis in eyes with a Boston Keratoprosthesis (KPro). METHODS A retrospective chart review was performed for 255 eyes of 231 patients who received a KPro between March 1990 and December 2006. Preoperative diagnoses were burn, ocular cicatricial pemphigoid (OCP), Stevens-Johnson Syndrome...

A case of pseudomonas endophthalmitis after penetrating keratoplasty is described. Bacterial sensitivities in this case and in five of six previously reported cases of endophthalmitis after corneal transplant showed resistance to gentamicin, an antibiotic routinely used in the transport medium. The recovery of antibiotic resistant bacteria in antibiotic supplemented media is discussed with emph...

Conventional microbiological culture techniques are frequently insufficient to confirm endophthalmitis clinical cases which could require urgent medical attention because it could lead to permanent vision loss. We are proposing PCR-DGGE and 16S rRNA gene libraries as an alternative to improve the detection and identification rate of bacterial species from endophthalmitis cases.

To report a case of bilateral endophthalmitis as the initial presentation of bacterial meningitis in a young, immunocompetent Korean patient. A 35-year-old female with a one day history of bilateral swollen eyes, visual disturbance, headache, petechial skin rash, and nausea visited our clinic. She was diagnosed as having endogenous endophthalmitis associated with bacterial meningitis. Intraveno...

AIM To evaluate the efficacy of intravitreal dexamethasone co-administered with intravitreal antibiotics along with vitrectomy in the management of exogenous bacterial endophthalmitis. METHODS In a prospective randomised clinical trial, 63 patients (63 eyes) with suspected bacterial endophthalmitis (postoperative and post-traumatic) were treated with vitrectomy and intravitreal antibiotics an...

Endophthalmitis is an intraocular inflammation involving both posterior and anterior segments, caused by bacterial or fungal infections. Here, we present a case series of five cases presented to the National Referral Hospital from January December 2017. Five eyes were identified, including exogenous endogenous odontogenic causes. All managed with vitrectomy, intravitreal antibiotics, systemic a...

Postoperative endophthalmitis is a rare, albeit serious, complication of cataract surgery. Over the years, preoperative and operative measures, such as lid hygiene, appropriate surgical draping, and improved surgical technique, have all decreased the incidence of postoperative endophthalmitis. Commonly used prophylactic measures include preoperative topical, intracameral, and postoperative topi...