conclusions the bacterial isolates exhibited strong biofilm formation potential, while the extracts of acacia arabica significantly inhibited biofilm formation among the isolates and, therefore, could be executed in the development of cost-effective biofilm inhibitor medicines. results pseudomonas aeruginosa (kc417303-05), staphylococcus hemolyticus (kc417306), and staphylococcus hominis (kc417...

The environmental topology of complex structures is used by Escherichia coli to create traveling waves of high cell density, a prelude to quorum sensing. When cells are grown to a moderate density within a confining microenvironment, these traveling waves of cell density allow the cells to find and collapse into confining topologies, which are unstable to population fluctuations above a critica...

The peptide antibiotic sporangiomycin specifically inhibits protein synthesis when added to growing cultures of Bacillus subtilis. A study on the reactions for bacterial protein synthesis in cell-free systems has shown that sporangiomycin interferes with specific reactions responsible for peptide-chain elongation, while it has no effect on peptide chain initiation. The primary action of the ant...

Protein phosphorylation is a vital mechanism in the regulation of all processes in eukaryotic and prokaryotic cells. It is one of the most important of those post-translational modifications which allow proteins to reversibly change their enzymatic activity, cellular localization, oligomeric state, half-life and interaction partners. Protein phosphorylation is mainly used by bacteria to adapt t...

When culturing bacteria in artificial microhabitats, such as in microfluidic devices, microchambers and microreactors, the ecological and microbiological aspects must be considered. In such devices and experiments cells often live in structured environments that from an ecological viewpoint could be considered “patchy” (i.e. with strong spatial heterogeneities and variations in suitability for ...

A common feature of cationic peptides is that their site of action is at the membrane due to channel formation, and that they tend to possess strong selectivity towards their target membrane. For example, although moth cecropin and bee melittin are members of the same family of peptides that adopt amphipathic a-helical structures, the cecropins are strongly antibacterial and demonstrate minimal...

Signaling in bacterial chemotaxis is mediated by several types of transmembrane chemoreceptors. The chemoreceptors form tight polar clusters whose functions are of great biological interest. Here, we study the general properties of a chemotaxis model that includes interaction between neighboring chemoreceptors within a receptor cluster and the appropriate receptor methylation and demethylation ...